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成人急性白血病患者血小板输注阈值和品种对止血效果的影响 被引量:2

Hemostatic Effect of Platelet Transfusion in 126 Adult Patients with Acute Leukemia
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摘要 目的探讨成人急性白血病患者血小板输注阈值和品种对止血效果的影响。方法选取施行血小板输注治疗的成人急性白血病患者126例,按照输注前患者血小板计数(PLT)分为A组(20×109/L<PLT<50×109/L)、B组(10×109/L<PLT≤20×109/L)、C组(5×109/L<PLT≤10×109/L)、D组(PLT≤5×109/L)共4组,分别统计每组输注的血小板品种、输注后止血效果,分析它们之间的相互关系。结果 C组血小板输注后止血效果明显好于其他3组(P<0.05);根据输注的血小板品种的不同作比较,D组输注手工血小板的止血效果明显好于单采血小板(P<0.05),其余3组输注手工血小板和单采血小板的止血效果差异无统计学意义(P>0.05)。结论成人急性白血病输注血小板的止血效果与输注前血小板计数及血小板品种有明显相关性。 Objective To analyze platelet transfusion in 126 patients with acute leukemia was performed to explore the relationship among platelet transfusion threshold,varieties and hemostatic effect after infusion. Methods According to the platelet count( PLT) of patient before platelet infusion,126 adult patients with acute leukemia were selected to be divided into group A( 20 × 10^9/L〈 PLT〈 50 × 10^9/L),group B( 10 × 10^9/L 〈PLT≤20 × 10^9/L),group C( 5 × 10^9/L〈 PLT≤10 × 10^9/L) and group D( PLT≤5 × 10^9/L). Platelet varieties and hemostatic effect after infusion in each group were analyzed respectively to discovered their relationship. Results According to the different comparison of PLT,the hemostatic effect of patients in group C is significantly better than patients in other three groups( P 0. 05); According to the type of platelet,the hemostatic effect of patients with manual platelet was platelet was obviously better than patients with apheresis platelets in group D( P〈0. 05). In other three groups,the hemostatic effect of manual platelets has no significant changes compared with apheresis platelets of each group( P〉0. 05). Conclusion The hemostatic effect of platelet transfusion was typically associated with the platelet count and the type of platelet in acute leukemia.
出处 《医疗装备》 2017年第12期1-2,共2页 Medical Equipment
基金 西南医科大学附属医院青年基金项目(11200)
关键词 急性白血病 血小板输注 止血效果 阈值 Acute leukemia Platelet transfusion Hemostatic effect Threshold value
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