摘要
目的了解Sweet综合征的临床及组织病理特点。方法回顾性分析本院2010-2016年诊治的25例Sweet综合征患者的临床和组织病理资料。结果 25例患者发病年龄32~78岁,女16例,男9例,夏季易发。皮损皆表现为鲜红色或暗红色结节或斑块,多发16例,单发9例,8例皮疹伴疼痛。7例可见假水疱,2例出现水疱。5例伴发热,其中3例伴眼结膜充血,2例伴关节酸痛。组织病理:25例均表现为真皮乳头层的水肿,真皮浅层的中性粒细胞浸润及核尘。全部25例经系统糖皮质激素治疗痊愈。结论 Sweet综合征临床表现差异较大,容易误诊,组织病理出现的真皮乳头层的水肿,真皮浅层的中性粒细胞浸润及核尘,对诊断Sweet综合征的特异性较高。本病对糖皮质激素治疗比较敏感。
Objective Summarize and analyze the clinical and histopathological data of Sweet syndrome cases. Methods Retrospective analysis was made based on 25 cases of Sweet syndrome in our hospital between year 2010 to 2016. Results The patients aged from 32 to 78 years,with 16 females and 9 males. Most of the cases came to my hospital in summer. All 25 cases had skin lesions, 16 cases had more than 1 lesion, 8 cases had pain in skin lesions. False blisters were seen in 7 cases, blisters were seen in 2 cases. 5 cases had fever, among which, 3 also had conjunctival congestion, 2 also had arthralgia. Histopathology： papilla edema, neutrophil infiltration and nuclear dust in the upper dermis could be seen in all the 25 cases. All the cases were cured with systemic corticosteroid treatment. Conclusion The clinical features of Sweet syndrome cases vary in a big range, thus may be misdiagnosed. Histopathological evidence is most important in the diagnosis of Sweet syndrome. Sweet syndrome is sensitive to systemic corticosteroid treatment.
出处
《中国皮肤性病学杂志》
CSCD
北大核心
2017年第7期746-748,共3页
The Chinese Journal of Dermatovenereology
