摘要
目的探讨液基细胞学检测(TCT)在宫颈癌筛查中的应用效果。方法选取2015年6月至2016年12月间眉山市妇幼保健院收治的760例宫颈筛查患者,所有患者均行TCT检测,对于TCT阳性的患者行阴道镜检测,以病理诊断为金标准,观察分析TCT检测的准确度和特异度。结果760例患者中液基细胞学异常者159例(20.9%),其中不典型鳞状细胞(ASCUS)75例(9.9%),高度鳞状上皮内病变(HSIL)43例(5.7%),低度鳞状上皮内病变(LSIL)41例(5.4%)。159例患者阴道镜下宫颈活检术发现,宫颈上皮内瘤变(CIN)I患者73例(45.9%)。在75例ASCUS患者中,阴道镜检查CIN I 41例,CIN II 18例,TCT诊断符合率为78.7%;43例HSIL患者中,阴道镜检查CIN I14例,CIN II 18例,CIN III 6例,3例宫颈癌,符合率为95.3%;41例LSIL患者中,阴道镜检查CIN I18例,CIN II 13例,CIN III 3例,符合率为82.9%。结论 TCT检查在宫颈癌筛查中准确度较高,可为临床诊断提供一定的依据。
Objective To explore the efficacy of liquid-based cytology for screening cervical cancer. Methods Seven hundred and sixty patients who had cervical screening tests at Meishan Maternal and Child Health Care Hospital from June 2015 to December 2016 were selected. All patients underwent liquidbased cytology test. The patients with positive liquid-based cytology test results were examined by colposcopy. Pathology test results were considered as the gold standerd to analyze the accuracy and specificity of liquid-based cytology. Results Among the 760 patients,159 patients（20. 9%） were found to have abnormal liquid-based cytology,among which 75（9. 9%） were atypical squamous cells（ASCUS）,43（5. 7%）were of high grade squamous intraepithelial lesion（HSIL） and 41（5. 4%） were low grade squamous intraepithelial lesion（LSIL）. Among the 159 patients who underwent colposcopy examination,cervical intraepithelial neoplasia（CIN） I was found in 73（45. 9%） patients. Among 75 ASCUS patients,colposcopy examination suggested that CIN I occurred in 41 patients,CIN II occurred in 18 patients and the coincidence rate of liquid-based cytology was 78. 7%. Among 43 HSIL patients,colposcopy examination suggested that CIN I occurred in 14 patients,CIN II in 18 patients and CIN III in 6 patients,and the coincidence rate of liquid-based cytology was 95. 3%. Among 41 LSIL patients,colposcopy examination suggested that CIN I occurred in 18 patients,CIN II in 13 patients and CIN III in 3 patients,and the coincidence rate of liquidbased cytology was 82. 9%. Conclusion Liquid-based cytology showed high accuracy in cervical cancer screening,which can provide some evidence for clinical practice.
出处
《中国肿瘤临床与康复》
2017年第6期695-697,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
液基细胞学检测
阴道镜检查
宫颈肿瘤
筛查
Liquid-based cytology test
Colposcopy test
Cervical neoplasms
Screening
