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奈达铂:一种铂类抗癌新药 被引量:22

Nedaplatin: a New Anticancer Platinum Agent
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摘要 奈达铂 (NDP)是第二代铂类化合物 ,研究表明其抗肿瘤作用优于顺铂 ,毒性谱有异。综述 NDP的临床前研究及临床应用 ,着重评述其单用或与其他抗癌药联用治疗头颈部癌、食管癌、肺癌和生殖系肿瘤的疗效。 Nedaplatin (NDP)is a platinum compound of second generation. It was demonstrated that its anticancer activity is superior to cisplatin. The preclinical reaserch and clinical applicatin of NDP were reviewed and its efficacy on head and neck, oesophagus, lung, and genital cancer in either single administration or combination with other anticancer agents were emphasized.
机构地区 湖南省肿瘤医院
出处 《药学进展》 CAS 2002年第4期223-226,共4页 Progress in Pharmaceutical Sciences
关键词 奈达铂 铂类抗癌新药 抗肿瘤谱 临床应用 NDP Nedaplatin Anticancer spectrum Clinical application
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  • 1[1]Lebwohl D , Canetta R. Clinical development of platinum complexes in cancer therapy: an historical perspective and an update[J]. Eur J Cancer, 1998,34(10): 1522-1534.
  • 2[2]Muramatsu S, Ku Y, Kuroda Y. Pharmaeokinetic comparison between cisplatin and nedaplatin in hepatic arterial chemotherapy using complete hepatic venous isolation and charcoal hemoperfusion[J]. Jpn J Cancer Chemother,1998,25(9): 1457-1460.
  • 3[3]Kawanishi K, Miyagi Y, Yamamoto J, et al. Cytocidal effect and DNA damage of nedaplatin in vitro by simulating pharmacokinetic parameters[J]. Cancer Chemother Pharmacol,2001,47(4): 303-308.
  • 4[4]Fujii M, Tokumaru Y, Imanishi Y, et al. Combination chemotherapy with nedaplatin and 5-FU for head neck cancer[J]. Jpn J Cancer Chemother, 1998, 25(1):53-58.
  • 5[5]Sasaoka M, Fuua N, Matsumoto A, et al. Alternating chemoradiotherapy for oropharyngeal cancer [J]. Jpm J Cancer Chemother, 2000; 27(14): 2217-2221.
  • 6[6]Takeda Y, Kasai H, Uchida N, et al. Enhanced antitumor efficacy of nedaplatin with 5-fluorouracil against human squamous carcinoma xenografts [J]. Anticancer Res, 1999,19 (5B): 4059-4064.
  • 7[7]Yoshioka T, Gamoh M, Shineha R, et al. A new combimation chemotherapy with cis- diammine- glycolatoplatinum (nedaplatin) and 5-fluorouracil for advanced esoiphageal cancers[J]. Intern Med, 1999, 38(11) :844-848.
  • 8[8]Hirata S, Yatsuyanagi E, Yamazaki H, et al. Neoadjuvant chemotherapy for esophageal cancer by administration of nedaplatin alone[J]. Jpm J Cancer Chemother, 2000, (2):221-226.
  • 9[9]Sumi H, Ohtsu A, Boku N, et al. A case of inoperable esophageal carcinoma with hepatic and nodal metastases which showed a long-term survival after chemradiotherapy including nedaplatin[J]. Jpn J Clin Oncol, 2000, 30(9):406-409.
  • 10[10]Matsumoto M, Takeda Y, Maki H, et al. Preclinical in vivo antitumor efficacy of nedaplatin with gemcitabine against human lung cancer[J]. Jpn J Cancer Res, 2001, 92 (1):51-58.

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