摘要
目的:观察分阶段辨证联合针灸疗法、心理干预的综合治疗方法治疗慢性乙型肝炎肝纤维化的临床疗效。方法:医院收治的慢性乙型肝炎肝纤维化患者120例纳入本项研究,使用随机方法按照1∶1分为综合治疗组和对照组,每组各60例。两组均给予恩替卡韦片抗病毒治疗,治疗6个月。对照组给予复方鳖甲软肝片,综合治疗组在口服恩替卡韦治疗基础上用分阶段辨证施治联合针灸疗法、心理干预治疗。观察两组治疗前后中医征候积分、肝功能指标、肝纤维化四项及B型超声指标(门静脉内径、脾脏厚度)。结果:综合治疗组患者治疗的总有效率为86.7%,明显高于对照组的65%,差异具有统计学意义(P<0.05)。与对照组相比,综合治疗组治疗后中医征候积分、肝功能指标、肝纤维化指标及B型超声指标改善更明显,差异均有统计学意义(P<0.05)。结论:分阶段辨证联合针灸疗法、心理干预的综合治疗方法应用于慢性乙型肝炎肝纤维化有助于延缓肝纤维化进程,改善肝功能。
Obiective：To investigate clinical effects of syndrome differentiation in stages, acupuncture therapy and heart intervention on hepatitis B liver fibrosis. Methods ： A total of 100 cases of hepatitis B liver fifbrosis patients were di- vided into the comprehensive treatment group and control group, 60 case in each group. Control group was given oral en- tecavir（ 1 tablet/times, 1 time/day）, Fufang Biejia Ruangan Tablets （4 tablets/time, three times/day）. Besides ente- cavir,patients in the comprehensive treatment group received syndrome differentiation in stages, acupuncture therapy and heart intervention. After treatment,liver function, liver fibrosis and type B ultrasonic indicators were compared. Results ： The total effective rate of the comprehensive treatment group was 86.7%, significantly higher than that of the control group （65 % ） （P 〈 0. 05）. The liver function, liver fibrosis and type B ultrasonic indicators in comprehensive treatment group were improved than those of control group （ P 〈 0. 05 ）. Conclusion ： The comprehensive treatment of syndrome differ- entiation in stages, acupuncture therapy and heart intervention is helpful to hepatitis B liver fibrosis parents in delaying the process of liver fibrosis and improving liver function.
出处
《中华中医药学刊》
CAS
北大核心
2017年第7期1687-1690,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家中医药管理局科技计划项目(2013ZX10005002-001)
关键词
肝纤维化
中医药
辨证
肝炎
心理干预
针灸
liver fibrosis
traditional Chinese medicine
syndrome differentiation
hepatitis B
heart Intervention
acu- puncture therapy
