摘要
目的:分析莫西沙星治疗老年社区获得性肺炎的临床疗效和安全性。方法:2015年5月~2016年6月一共收治60例老年社区获得性肺炎患者,随机分组,对照组采用莫西沙星以外的抗生素联合用药方案,观察组采用莫西沙星静脉注射和口服联合治疗方案,比较两组治疗有效率、临床症状消失时间、不良反应发生情况。症状包括发热、咳嗽、肺啰音等等。结果:(1)对照组治疗有效率为60%,观察组治疗有效率(93.33%)明显高于对照组,差异具有统计学意义,P<0.05。(2)与对照组(25.05±3.55、38.55±6.55、25.05±3.85、28.50±5.05、35.05±5.55)对比,观察组退热时间(5.01±1.05)d、咳嗽咳痰消失时间(20.03±0.80)d、肺部啰音消失时间(15.05±1.85)d、抗生素使用时间(16.03±2.91)d、住院时间(15.05±3.05)d明显更短,差异具有统计学意义,P<0.05。(3)与对照组(43.33%)对比,观察组不良反应发生率(6.67%)明显更低,差异具有统计学意义,P<0.05。结论:莫西沙星治疗老年社区获得性肺炎的临床疗效显著,安全性良好,不良反应少,值得临床广泛应用以及推广。
Objective： To analyze the efficacy and safety of moxifloxaein in the treatment of community-acquired pneumonia in the elderly.Methods： From May 2015 to June 2016, 60 elderly patients with community acquired pneumonia were randomly divided into two groups. The control group was treated with moxifloxacin combined with other antibiotics. Moxifloxacin combined with oral moxifloxacin was used in the observation group Program, comparing the two groups of patients with effective treatment, the disappearance of clinical symptoms of time, adverse reactions. Symptoms include： fever, cough, lung tales and so on.Results： （1）The effective rate was 60% in the control group and 93.33% in the observation group. The difference was statistically significant （P〈0.05）. （2）Compared with the control group （25.05±3.55,38.55±6.55,25.05±3.85,28.50±5.05,35.05±5.55）, the time of fever, the time of cough and expectoration disappeared in the observation group was 5.01±1.05d,20.03±0.80d, The time of disappearance of the rales was 15.05±1.85 days, the use time of antibiotics was 16.03±2.91 days, and the hospitalization time was 15.05±3.05 days. The difference was statistically significant （P〈0.05）.（3）Compared with the control group （43.33%）, the adverse reaction rate （6.67%） in the observation group was significantly lower than that in the control group （P〈0.05）.Conclusion： Moxifloxaein treatment of community-acquired pneumonia in elderly patients with clinical efficaey, safety, good, less adverse reactions, it is widely used in clinical and promotion.
作者
韦杰
尹迎秋
Wei Jie Yin Yingqiu(Shaoguan, guangdong, guangdong, guangdong, guangdong province, 512026)
出处
《北方药学》
2017年第7期126-127,共2页
Journal of North Pharmacy
关键词
莫西沙星
老年社区获得性肺炎
临床疗效
安全性
Moxifloxaein Community-acquired pneumonia in the elderly Clinieal efficacy Safety
