摘要
目的:评价阿米替林对带状疱疹患者神经痛的临床效果。方法:选取2014年8月—2016年8月期间收治的带状疱疹神经痛患者82例作为研究对象,将其随机分为观察组41例和对照组41例;对照组患者给予卡马西平治疗,观察组患者在对照组患者治疗基础上给予阿米替林治疗,评价两组患者治疗后的总有效率。结果:观察组患者治疗2周、3周、4周后经视觉模拟量表(VAS)和睡眠治疗评分法(QS)的疼痛评分值均低于对照组(P<0.05);观察组患者治疗3周、4周后睡眠质量评分值均低于对照组(P<0.05),治疗的总有效率高于对照组(P<0.05)。结论:阿米替林用于治疗带状疱疹患者神经痛的临床疗效较好,能有效改善患者的临床症状。
Objective： To evaluate the clinical efficacy ofamitriptyline in postherpetic neuralgia patients with shingles. Methods： during August 2014 to August 2016, selecting the neuralgia patients with shingles, 82 patients were randomly divided into two groups（41 cases in observation group and 41 cases in the control group）; the control group were treated with carbamazepine therapy, the patients in the observation group were treated with amitriptyline besides the treatment in the control group. Results： After the patients in the observation group were treated for 2 weeks, 3 weeks and 4 weeks the pain scores were lower than the control group; there was statistical significance （P〈0.05）; after the pa- tients in the observation group were treated for 3 weeks and 4 weeks sleep quality scores were lower than the control group and there was statistical significance （P〈0.05）; the treatment efficiency of observation group was statistically higher than the control group. The significance was P〈0.05. Conclusion： Amitriptyline is used in the treatment of neuralgia patients with shingles, the clinical efficacy is better, and the patient＇s clinical symptoms can be effectively improved.
出处
《抗感染药学》
2017年第3期597-599,共3页
Anti-infection Pharmacy
关键词
阿米替林
带状疱疹神经痛
临床效果
amitriptyline
carbamazepine
shingles
clinical efficacy
postherpetic neuralgia patients with shingles
