摘要
目的研究不同年龄髋关节置换术患者术后谵妄与认知功能障碍发生情况及相关性。方法选取我院行髋关节置换术的300例患者,根据年龄分为老年组(172例)与非老年组(128例),均采用腰麻-硬膜外联合麻醉。比较两组患者的手术时间、术中出血量、术中输液量、术后谵妄及认知障碍的发生率。结果两组患者的手术时间、术中出血量和术中输液量比较差异均无统计学意义(P>0.05)。老年组的术后谵妄及认知功能障碍发生率分别为32.56%、12.79%,显著高于非老年组的16.41%、3.13%(P<0.05)。两组患者的术后谵妄发生时间比较差异无统计学意义(P>0.05)。Spearman相关分析显示,术后谵妄与认知功能障碍发生率呈正相关(P<0.05)。结论髋关节置换术老年患者术后谵妄及认知功能障碍发生率明显高于非老年患者,术后谵妄与认知功能障碍密切相关,术后早期发生谵妄可能是引起认知功能障碍的危险因素之一。
Objective To study the delirium and cognitive dysfunction in different ages of patients after hip replacement and the correlation. Methods 300 cases of patients undergoing hip replacement in our hospital were selected and divided into elderly group （172 cases） and non-elderly group （128 cases） according to their ages. All patients received combined epidural-spinal anesthesia. The operation time, intraoperative blood loss, intraoperative transfusion volume, incidences of postoperative delirium and cognitive dysfunction were compared between two groups. Results No statistical difference was found in the operation time, intraoperative blood loss and intraoperative transfusion volume between two groups （P〉0.05）. The incidences of postoperative delirium and cognitive dysfunction of elderly group were respectively 32.56% and 12.79 %, significantly higher than 16.41% and 3.13 % of non-elderly group （.P 〈0.05）. No statistical difference was found in the time of postoperative delirium between groups （P 〉0.05）. Spearman correlation analysis showed that the incidence of postoperative delirium was positively correlated with that of cognitive dysfunction （P 〈0.05）. Conclusions The incidences of postoperative delirium and cognitive dysfunction of elderly patients undergoing hip replacement are significantly higher than those of non-elderly patients. Postoperative delirium is closely correlated with cognitive dysfunction. Postoperative early delirium may be one of the risk factors that causing cognitive dysfunction.
出处
《临床医学工程》
2017年第7期973-974,共2页
Clinical Medicine & Engineering
