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钛种植体表面生物改性的研究进展 被引量:3

Research progress in titanium dental implant biological modification
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摘要 目前,种植体表面改性技术已基本形成较成熟的物理及化学改性体系。但钛是一种生物惰性材料,直接植入体内后不能与骨组织快速形成化学键合,可一定程度影响种植的成功率。因此,学者们在钛种植体表面引入一些可直接作用于骨细胞及周围组织的生物活性物质,通过生物活性物质的调控和促进作用,使种植体与骨组织能在短期内形成较好的骨结合。这类生物改性技术是近年种植领域的研究热点,起步较晚,目前尚未形成较完善的体系。本文对目前生物改性的主要活性物质和方法以及生物改性的研究现状及发展趋势做一综述。 During the past three decades, the technology of implant surface modification has already formed well-developed methods including physical and chemical means. However, titanium is a kind of bioinert material, which will directly result in slowly bone-bond with bone tissue after implantation and ultimately reduce the success rate of dental implant surgery. Therefore, the introduction of bioactive substances which can effectively regulate and promote the proliferation of bone cells to modify the titanium implant surface has received tremendous attention in the research of oral implant field. The research of biological modification starts relatively late and it has not formed well-established system yet. The research progress is given in this paper concerning the bioactivators and methods used in biological modification. Furthermore, the current situation as well as the recent developments involving the biological modification of dental implant are also discussed in this review.
作者 夏一菁 赵彬
出处 《中华口腔医学杂志》 CAS CSCD 北大核心 2017年第7期450-453,共4页 Chinese Journal of Stomatology
基金 山西省国际科技合作项目(2014081058)
关键词 牙种植 生物改性 Dental implantation Titanium Biological modification
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  • 1战德松,赵宝红,田维明,崔福斋.RGD修饰纯钛表面对人牙龈成纤维细胞生物学行为的影响[J].材料研究学报,2005,19(3):320-324. 被引量:7
  • 2赵宝红,战德松,田维明,崔福斋,冯海兰.RGD修饰钛表面对人牙龈成纤维细胞初期黏附和铺展的影响[J].材料研究学报,2005,19(4):369-374. 被引量:5
  • 3何曼君,张红东,陈维孝,等.高分子物理[M].3版.上海:复旦大学出版社,2009.
  • 4Saju KK, Jayadas NH, Vidyanand S, et al. Investiga- tions into the molecular-level adhesion characteristics of hydroxyapatite-coated and anodized titanium surfaces using the molecular orbital approach[J] Proc Inst Mech Eng H, 2011,225(3):246-254.
  • 5Pegueroles M, Aguirre A, Engel E, et al. Effect of blasting treatment and Fn coating on MG63 adhesion and differentiation on titanium: a gene expression study using real-time RT-PCR[J]. J Mater Sci Mater Med, 2011, 22(3):617-627.
  • 6Ryu J J, Park K, Kim HS, et al. Effects of anodized titanium with Arg-GIy-Asp(RGD) peptide immobi- lized via chemical grafting or physical adsorption on bone cell adhesion and differentiation[J]. Int J Oral Maxillofac Implants, 2013, 28(4):963-972.
  • 7Park JW, Kurashima K, Tustusmi Y, et al. Bone healing of commercial oral implants with ROD im- mobilization through electrodeposited poly(ethylene glycol) in rabbit cancellous bone[J]. Acta Biomater, 2011, 7(8):3222-3229.
  • 8Hwang DS, Waite JH, Tirrell M. Promotion of osteo-blast proliferation on complex coacervation-based hyaluronic acid-recombinant mussel adhesive protein coatings on titanium[J]. Biomaterials, 2010, 31(6): 1080-1084.
  • 9Chen M, Wu C, Song D, et al. Effect of grooves on adsorption of RGD tripeptide onto rutile TiO(2) (110) surface[J]. J Mater Sci Mater Med, 2009, 20 (9):1831-1838.
  • 10Maddikeri RR, Tosatti S, Schuler M, et al. Reduced medical infection related bacterial strains adhesion on bioactive RGD modified titanium surfaces: a first step toward cell selective surfaces[J]. J Biomed Mater Res A, 2008, 84(2):425-435.

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