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Ⅲ期非小细胞肺癌两种不同放疗技术在靶区和危及器官上的剂量差异比较

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摘要 目的:探讨Ⅲ期非小细胞肺癌(NSCLC)两种不同放疗技术在靶区和危及器官上的剂量差异。方法:选择2014年9月至2015年9月广东省中医院收治的Ⅲ期NSCLC患者60例,将其随机分为两组,各30例。对照组采用三维适形放疗(3D-CRT),观察组给予调强放疗(IMRT)。对比两组靶区剂量分布情况与危及器官剂量学参数。结果:两组计划靶区剂量分布参数相比,差异无统计学意义(P>0.05);观察组适形指数(CI)明显低于对照组,而异质性指数(HI)明显高于对照组,差异有统计学意义(P<0.05);观察组心脏V35、脊髓Dmean等剂量参数均明显低于对照组,差异有统计学意义(P<0.05)。结论:IMRT较3D-CRT有助于改善靶区适形度,控制危及器官上剂量,对正常组织进行有效保护,改善患者预后。
机构地区 广东省中医院
出处 《深圳中西医结合杂志》 2017年第8期60-62,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
基金 广东省科技厅自筹经费类项目资助课题(201507)
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