摘要
目的探讨负压封闭引流技术(VSD)应用四肢软组织缺损伴感染患者的临床治疗效果和对组织局部供血的影响。方法选取在2014年2月-2016年9月医院的四肢软组织缺损感染患者的71例进行分析,随机分为常规组35例和研究组36例,两组患者均进行清创术处理后,常规组患者采取常规换药方法,而研究组患者选择负压封闭引流术作为治疗方法,对两组患者的抗感染时间、住院时间、换药次数、抗菌药物使用时间及局部供血情况比较分析,并观察在治疗1天、5天、10天患者的疼痛程度,以及比较两组患者的创面愈合时间、愈合病例,治疗有效率,并发症发生情况和不良反应发生率。结果研究组患者的感染治疗时间为(11.46±1.85)d、住院时间为(50.53±4.31)d、换药次数(1.79±0.58)次、抗菌药物使用时间(3.64±1.12)d、创口愈合时间(30.42±2.76)d,均明显少于常规组;研究组患者的局部平均血流量(46.81±9.45)mV,明显高于常规组的平均血流量(23.96±5.73)mV;疼痛程度按照SF-MPQ疼痛评分法,研究组患者在1天(5.08±0.73)分、5天(3.97±1.06)分、10天(1.23±0.89)分的疼痛评分均低于常规组;研究组治疗有效率为97.22%明显高于常规组;研究组患者的并发症发生率为2.78%、不良反应发生率为5.56%明显低于常规组,以上数据两组比较差异均有统计学意义(P<0.05)。结论负压封闭引流技术在治疗四肢软组织缺损并创面感染患者时,具有更确切的疗效,能够缩短治疗和抗感染时间,加速创口愈合,对于感染的控制和临床治疗效果比传统换药治疗具有明显的优势。
OBJECTIVE To explore the clinical effect of vacuum sealing drainage（VSD）on treatment of limb soft tissue defect patients complicated with infection and observe the influence on local tissue blood supply.METHODS A total of 71 limb soft tissue defect patients complicated with infection who were treated in the hospital from Feb2014 to Sep 2016 were enrolled in the study and randomly divided into the conventional group with 35 cases and the study group with 36 cases.After the debridement,the conventional group was treated with conventional drug dressing,while the study group was given VSD.The anti-infection time,length of hospital stay,time of dressing change,time of use of antibiotics,and status of local blood supply were compared between the two groups of patients,the pain degree was observed on Day 1,5,and 10 of treatment,and the wound healing time,number of cases of healing,effective rate of treatment,and incidence of complications and adverse reactions were compared between the two groups of patients.RESULTS The time of treatment of infections of the study group was（11.46±1.85）days,shorter than that of the conventional group;the length of hospital stay of the study group was（50.53±4.31）days,significantly shorter than that of the conventional group;the number of times of dressing change of the study group was（1.79±0.58）times,significantly less than that of the conventional group;the time of use of antibiotics of the study group was（3.64±1.12）days,significantly shorter than that of the conventional group;the wound healing time of the study group was（30.42±2.76）days,remarkably shorter than that of the conventional group.The mean local blood flow of the study group was（46.81±9.45）mV,higher than（23.96±5.73）mV of the conventional group.The pain degree was determined on the basis of the SF-MPQ pain scoring method,the pain scores of the study group were respectively（5.08±0.73）points,（3.97±1.06）points,and（1.23±0.89）points on Day 1,5,and 10 of treatment,lower than those of the conventional group.The effective rate of treatment of the study group was 97.22%,significantly higher than that of the conventional group.The incidence of complications of the study group was 2.78%,significantly lower than that of the conventional group;the incidence of adverse reactions of the study group was 5.56%,significantly lower than that of the conventional group（P〈0.05）.CONCLUSION VSD,as is used for treatment of the limb soft tissue defect patients complicated with wound infections,can achieve more exact effect,shorten the treatment and anti-infection time,and accelerate the wound healing.It has more remarkable advantages on control of infections and clinical therapeutic effect than the conventional dressing change.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2017年第13期3040-3043,共4页
Chinese Journal of Nosocomiology
关键词
负压封闭引流
四肢软组织缺损
创面感染
局部供血
临床效果
Vacuum sealing drainage
Limb soft tissue defect
Wound infection
Local blood supply
Clinical effect
