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糖尿病肾病治疗临床试验的研究进展 被引量:21

Research Progress of Clinical Trials for the Treatment of Diabetic Nephropathy
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摘要 糖尿病肾病是糖尿病患者常见的并发症之一,严重危害公众健康。尽管肾素-血管紧张素(RAS)拮抗剂、降压、降糖等治疗能够延缓糖尿病肾病的进展速度,但目前尚缺乏针对其发病机制的有效治疗,部分患者仍会进展至终末期肾病(ESRD)。为了给糖尿病肾病患者的临床治疗提供更多选择,本文就近期发表的临床随机对照试验进行综述。 Diabetic nephropathy( DN) is one of the common complications of diabetes mellitus that threatens human health severely. Although existing interventions such as inhibition of the renin-angiotensin system( RAS), lowering hypertension and hyperglycemia have been shown to slow the progression of DN,no treatments are directed at its pathogenesis effectively. Some patients may still progress to end-stage renal disease( ESRD) ultimately. In order to offer more clinical options for DN management,we summarized the recent findings demonstrated in randomized controlled clinical trials.
作者 许倬 涂晓文 曹海丽 XU Zhuo TU Xiao-wen CAO Hai-li(Department of Nephrology, the General Hospital of the PLA Rocket Force, Beijing 100088, China)
出处 《中国全科医学》 CAS 北大核心 2017年第20期2535-2538,共4页 Chinese General Practice
关键词 糖尿病肾病 临床试验 综述 Diabetic nephropathy Clinical trial Review
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