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原发性闭角型青光眼房水中促炎症因子升高机制的研究进展 被引量:8

Mechanism of elevated proinflammatory cytokines in aqueous humor of patients with primary angle-closure glaucoma
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摘要 青光眼是一组以特征性视神经萎缩和视野缺损为共同特征的疾病,是世界上第二位致盲性眼病。原发性闭角型青光眼是我国原发性青光眼中最常见的类型,关于其发病机制目前有很多学说,如机械学说和血管学说。而近几年研究发现,炎症反应可能也参与了青光眼的发病过程,原发性闭角型青光眼患者房水中多种促炎症因子显著升高。本文总结了两种常用的房水因子的检测方法。 Glaucomais a group of diseases characterized by optic atrophy and visual field defect.In China,primary angle closure glaucoma (PACG) is the most common type of glaucoma.The mechanism of glaucoma has many theories,such as mechanical theory and vascular theory.Recent researches found that inflammation may be involved in the pathogenesis of glaucoma.A variety of proinflammatory cytokines significantly increased in aqueous humor of patients with PACG.In this study,we summarized the methods for the detection of aqueous humor,and analyzed the mechanism of the increasing of proinflammatory cytokines in the aqueous humor of patients with PACG.
作者 张勇 谢琳 Yong Zhang Lin Xie(Department of Ophthalmology, the Third Affiliated Hospital of Third Military Medical University, Chongqing 400042, Chin)
出处 《国际眼科杂志》 CAS 2017年第8期1465-1468,共4页 International Eye Science
关键词 原发性闭角型青光眼 房水 促炎症因子 primary angle-closure glaucoma aqueous humor proinflammatory cytokine
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