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抗-CCP和RF联合检测对RA的临床诊断价值探讨

Clinical Value of Combined Detection of-CCP and RF in the Diagnosis of RA
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摘要 目的分析抗环瓜氨酸肽抗体与类风湿因子联合检测对类风湿性关节炎的临床诊断效果。方法选2014年10月至2016年12月在广东省茂名市电白区中医院就诊的类风湿性关节炎患者100例(研究组),及同时期健康体检者100例(对照组)为研究对象,观察抗环瓜氨酸肽抗体与类风湿因子阳性检出率。结果研究组患者抗环瓜氨酸肽抗体与类风湿因子的阳性检出率均要高于对照组患者,两组数据之间进行比较,差异有统计学意义(P<0.05)。结论抗环瓜氨酸肽抗体与类风湿因子联合检测的灵敏度、特异度较高,是作为鉴别类风湿性关节炎疾病的重要指标,值得临床推广及应用。 Objective To analyze the clinical diagnosis of rheumatoid arthritis combined with anti - cyclic citrullinated peptide antibody and rheumatoid factor. Methods Sixty patients ( study group) with rheumatoid arthritis were enrolled in our hospital from October 2014 to December 2016, and 60 healthy subjects (control group) were selected as the study subjects. Citrate antibody and rheumatoid factor positive detection rate. Results The positive rate of anti - cyclic citrullinated peptide antibody and rheumatoid factor in the study group was higher than that in the control group, and the difference between the two groups was statistically significant (P 〈 0. 05). Conclusion The sensitivity and specificity of anti - cyclic citrullinated peptide antibody combined with rheumatoid factor is an important index for the identification of rheumatoid arthritis disease, and it is worthy to be popularized and applied.
出处 《广东微量元素科学》 CAS 2017年第7期54-56,共3页 Trace Elements Science
关键词 抗环瓜氨酸肽抗体 类风湿因子 类风湿性关节炎 诊断价值 anti - cyclic citrullinated peptide antibody rheumatoid factor rheumatoid arthritis diagnostic value
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