摘要
目的通过描述卡马西平致老年三度房室传导阻滞病例的临床表现特点,探讨老年癫痫患者应用卡马西平时潜在的严重心律失常风险。方法报告2例老年癫痫患者服用卡马西平过程中出现三度房室传导阻滞的临床表现及紧急治疗过程,并结合相关文献进行讨论。结果两例患者均出现三度房室传导阻滞,病情危重。常规药物治疗效果差,明确病因后应用针对性治疗病情迅速缓解。结论老年人这一特殊年龄群体的生理、病理特点以及卡马西平作用的特殊性,提示我们在其应用过程中要注意监测患者心电生理情况,结合临床表现,及时调整治疗剂量。
Objective To investigate the mechanisms and characteristic of third degree atrioventricular block（ AVB） attack induced by carbamazepinein elderly patients with epilepsy. Methods Third degree AVB appeared in two cases of elderly patients with epilepsy taking carbamazepine was reported. Clinical presentation and emergent treatment was discussed based on literatures review. Results Severe third degree AVB happened on these two patients during carbamazepine using. Conventional treatment was not effective,clinical situation turned to better after pertinent treatment was applied. Conclusions Electrocardiogram should be monitored with the therapeutic dose timely adjusted for elderly patients with epilepsy when receiving carbamazepine because of their special pathological and physiological features.
出处
《中国心血管杂志》
2017年第3期194-197,共4页
Chinese Journal of Cardiovascular Medicine
