摘要
目的比较原发性与继发性反复自然流产妇女的流行病学特点。方法选取2014年1月-2015年6月在该院妇产科门诊就诊的139例反复自然流产患者为研究对象,根据既往是否有过正常妊娠分娩史分为对照组(继发性反复自然流产)与研究组(原发性反复自然流产),分别为36例、103例。分析两组患者年龄、体重、身高、体重指数(BMI)、停育次数、孕产史、病因构成及妊娠结局。结果研究组患者年龄、既往妊娠次数分别为(27.84±4.93)岁、(2.68±1.21)次,明显低于对照组[(30.85±3.04)岁、(3.85±1.19)次],差异有统计学意义(P<0.05);研究组封闭抗体阴性、染色体异常患者所占比例高于对照组,而其他病因患者所占比例低于对照组(P<0.05);两组身高、体重、BMI、结婚年龄、停育次数、抗磷脂抗体综合征患者所占比例、妊娠与再次流产、成功妊娠患者受孕方式、分娩方式相比,差异均无统计学意义(P>0.05)。结论在一般情况方面,原发性反复自然流产患者年龄、既往妊娠次数低于继发性反复自然流产患者,其余各项无明显差异;在病因方面,两者病因构成不同;在妊娠结局方面,两者未见明显差异。
Objective To compare the epidemiological characteristics in women with primary and secondary recurrent spontaneous abortion（RSA）.Methods A total of 139 RSA patients treated in the hospital from January 2014 to June 2015 were selected as research objects,then they were divided into control group（secondary RSA,36 cases） and research group（primary RSA,103 cases） according to complicating with normal pregnancy and delivery history or not.Age,weight,height,body mass index（BMI）,embryo growth arrest times,pregnancy history,etiological constitution,and pregnancy outcomes in the two groups were analyzed.Results Age and previous times of pregnancy in research group were（27.84±4.93） years old and（2.69±0.43） times,respectively,which were statistically significantly lower than those in control group [（30.85±3.04） years old and（3.62±0.81） times,respectively]（P〈0.05）.The proportions of patients with negative blocking antibody and chromosome abnormalities in research group were statistically significantly higher than those in control group（P〈0.05）;the proportions of patients with other causes in research group were statistically significantly lower than those in control group（P〈0.05）.There was no statistically significant difference in height,weight,BMI,marriage age,embryo growth arrest times,proportion of patients with antiphospholipid syndrome,pregnancy and abortion again,conception methods of successful pregnancy patients,and delivery modes between the two groups（P〉0.05）.Conclusion In general cases,age and previous pregnancy times of primary RSA patients are lower than those of secondary RSA patients,there is no significant difference in the other cases;from the point of etiology,the etiological constitution of primary RSA patients and secondary RSA patients are different;in the aspect of pregnancy outcome,there is no significant difference between them.
出处
《中国妇幼保健》
CAS
2017年第13期2977-2980,共4页
Maternal and Child Health Care of China
关键词
原发性反复自然流产
继发性反复自然流产
流行病学
特点
Primary recurrent spontaneous abortion
Secondary recurrent spontaneous abortion
Epidemiology
Characteristics
