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动态检测降钙素原和痰细菌培养在ICU重症感染患者中的临床意义 被引量:4

Clinical significance of dynamic detection of PCT and sputum bacterial culture in ICU patients with severe infection
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摘要 目的探讨动态检测血清PCT水平和痰培养结果在ICU重症感染患者中的临床运用价值。方法选取本院2014年6月-2016年6月收治的150例重症感染患者作为研究对象,根据痰培养结果分为痰培养阳性组和痰培养阴性组,动态监测2组患者PCT水平。结果痰培养阳性患者PCT水平为(7.67±0.42)ng/ml、PCT阳性率为94.6%、APACHEⅡ评分为20.93±3.17,均明显高于痰培养阴性患者,差异有统计学意义(P<0.05)。PCT升高0.5 pg/ml、APACHEⅡ上升5分是患者死亡的独立风险因素(P<0.05)。结论血清PCT水平和APACHEⅡ评分是重症感染患者死亡的独立风险因素,动态检测PCT水平,并进行APACHEⅡ评分有助于患者预后判断。 Objective To investigate the clinical application value of dynamic detection of serum PCT levels and sputum culture results in ICU patients with severe infection. Methods 150 cases of severe infection patients in our hospital from June 2014 to June 2016 were selected as the research objects,according to the results of sputum culture which were divided into positive group and negative group,and PCT levels of sputum culture between the two groups were conducted for dynamic monitoring.Results The level of PCT in patients with positive sputum culture was( 7. 67 ± 0. 42) ng/ml,PCT positive rate was 94. 6%,the APACHEⅡ score was 20. 93 ± 3. 17,which were significantly higher than that of patients with negative sputum culture,with the differences statistically significant( P 〈0. 05). PCT increased 0. 5 pg/ml and APACHEⅡ increased 5 points,which were the independent risk factors for death patients( P 〈0. 05). Conclusion Serum PCT level and APACHE Ⅱ score are independent risk factors for the death in patients with severe infection,so dynamic detection of PCT levels and APACHE Ⅱ score are helpful to the prognosis of patients.
出处 《中国卫生检验杂志》 CAS 2017年第13期1910-1911,1915,共3页 Chinese Journal of Health Laboratory Technology
关键词 痰培养 降钙素原 重症感染 临床预后 Sputum culture Calcitonin Severe infection Clinical prognosis
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