摘要
目的评价无痛经内镜逆行性胰胆管造影术（ERCP）的安全性。方法纳入2008年1月1日至2016年6月30日行无痛ERCP的患者和2005年1月1日至2007年12月31日行非无痛ERCP的患者（对照），采用卡方检验观察两组的疾病构成情况、术中出现的情况、手术成功率和并发症发生情况。结果共纳入14 724例行无痛ERCP的患者和2 102例行非无痛ERCP的患者。14 724例行无痛ERCP患者中，胆胰恶性疾病1 799例，胆胰良性疾病12 925例；441例（3.00%）术中出现一过性低氧血症，经加大给氧流量、抬起下颌、减少给药量后均可缓解。无痛ERCP组手术成功率为98.41%（14 490/14 724），高于非无痛ERCP组的97.34%（2 046/2 102），差异有统计学意义（χ2＝11.500，P＝0.001）。无痛ERCP组术后胰腺炎发生率为2.35%（346/14 724），低于非无痛ERCP组的3.85%（81/2 102），差异有统计学意义（χ2＝16.813，P〈0.01）。结论无痛ERCP是安全的，且可能有利于提高手术成功率，减少术后胰腺炎的发生率。
Objective To evaluate the safety of anesthesia endoscopic retrograde cholangio- pancreatography （ERCP） under general anesthesia. Methods From January 1st, 2008 to June 30th, 2016, patients underwent ERCP under general anesthesia were enrolled as anesthesia group and from January 1st, 2005 to December 31st, 2007, patients accepted ERCP without anesthesia were enrolled as control group. Chi-square test was performed to analyze disease composition, conditions during operation, success rate of operation and complications in these two groups. Results A total of 14 724 patients with ERCP under general anesthesia and 2 102 patients received ERCP without anesthesia were enrolled. In 14 724 patients with ERCP under general anesthesia, I 799 cases had malignant biliary and pancreatic diseases and 12 925 cases with biliary and pancreatic diseases. During the operation, transient hypoxemia occurred in 441 cases （3. 00%Z） and relieved by increasing oxygen flow, lower anesthetic dose or lifting lower jaw. The success rate of ERCP in the anesthesia group （98.41 %,14 490/14 724） was higher than that in the control group （97. 34%, 2 046/2 102）, and the difference was statistically significant （x^2 = 11. 500, P=0. 001）. The incidence rate of post-ERCP pancreatitis in the anesthesia group was 2. 35% （346/14 724）, which was lower than that in the control group （3.85%, 81/2 102）, and the difference was statistically significant （x^2 =16. 813, P〈0. 01）. Conclusion ERCP under general anesthesia is safe, which could increase the success rate of operation and reduce the incidence rate of post-ERCP pancreatitis.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2017年第7期458-461,共4页
Chinese Journal of Digestion
关键词
麻醉
胰胆管造影术
内镜逆行
并发症
Anesthesia
Cholangio-pancreatography,Endoscopic retrograde
Complication
