摘要
尾加压素Ⅱ(UⅡ)最早是从鱼脊髓尾部下垂体中分离出的一种生长抑素样环肽。随后在人体内发现UⅡ的特异性受体,一种孤立的G蛋白偶联受体GPR-14。UⅡ与肿瘤的发生发展具有密切关系,UⅡ及其受体在多种肿瘤细胞中均有表达,并且UⅡ对肿瘤细胞生长具有显著促进作用。
Urotensin Ⅱ（U Ⅱ ） is one of the earliest somatostatin peptide isolated from the fish tail pituitary in spinal cord.The specific receptor of U Ⅱ was found in the human body, an isolated G protein coupled receptor GPR-14.U Ⅱ is closely related to the occurrence and development of tumor, U Ⅱ and its receptor are expressed in a variety of tumor cells.and U.
出处
《中国药物经济学》
2017年第6期156-158,共3页
China Journal of Pharmaceutical Economics
