摘要
目的 分析并讨论高压氧配合治疗新生儿胆红素脑病的疗效.方法 从2012年5月至2016年11月,我院接收胆红素脑病患儿67例中,选取33例选择常规治疗的患儿设为对照组,另外34例在常规治疗的基础上接受高压氧配合治疗的患儿设为观察组,比较两组的治疗效果.结果 经过系统治疗,两组患儿症状基本得到缓解,观察组临床疗效总有效率（97.06%）显著高于对照组（69.70%）,差异具有统计学意义（P〈0.05）;观察组住院时间为（24.10±2.95）d,显著短于对照组（38.80±5.32）d（P〈0.05）;治疗后观察组胆红素水平为（86.80±12.65）μmol/L显著低于对照组的（122.70±24.49）μmol/L,NABA评分为（37.30±1.92）分,显著高于对照组的（31.60±2.63）分,差异具有统计学意义（P〈0.05）.结论 临床上对于新生儿胆红素脑病的治疗中,应用高压氧辅助,可显著提高治疗效果,缩短治疗时间,建议临床推广应用.
Objective To investigate the clinical effect of hyperbaric oxygenation in treatment of newborn bilirubin en- cephalopathy. Methods A total of 67 cases of newborns with bilirnbin encephalopathy in our hospital were selected as study objects. They were divided into two groups according to different treatment methods, 33 cases given conventional treatment and were set as control group, another 34 cases given hyperbaric oxygenation based on conventional treatment were set as observation group. The clinical effects of the two groups were compared. Results After treatment, symptoms of newborns in the two groups were significantly alleviated, the clinical curative effect rate of observation group was 97.06%, which was was significantly higher than 69.69% of the control group, the difference was statistically significant （/~〈0.05）; the observation group hospitalization time was （24.10±2.95） d, which was significantly shorter than （38.80±5.32） d of the control group （P〈 0.05）; the bilirubin level of the observation group was （86.80±12.65） I^mol/L, which was significantly lower than （122.70± 24.49） μmol/L of the control group, NABA score was （37.30±1.92）, which was significantly higher than （31.60±2.63） of the control group, the differences were statistically significant （P〈0.05）. Conclusion The application of hyperbaric oxygenation in treatment of newborn bilirubin encephalopathy can improve clinical effect, shorten treatment time ,which is worthy of wide application.
出处
《临床研究》
2017年第5期59-60,共2页
Clinical Research
关键词
高压氧
新生儿
胆红素脑病
hyperbaric oxygen
newborn
bilirubin encephalopathy
