摘要
目的了解新疆伊犁地区八县一市城镇居民入院患者碘缺乏区和碘充足区尿碘水平、甲状腺功能状况及相关甲状腺疾病特点。方法采用整群随机抽样方法选取2008-2015年新疆伊犁州友谊医院住院患者,调查对象为18岁以上常住(≥5年)人口,进行问卷调查、尿碘水平检测和甲状腺功能测定。结果亚临床甲减、甲减、甲亢、结节性甲状腺肿的患病率分别为0.38%、2.18%、1.53%和1.83%。男女患病率差异有统计学意义(P<0.05)。维吾尔族、汉族、哈萨克族三个民族患病率比较发现,哈族与汉族的患病率比较差异有统计学意义(P<0.05),维族与汉族患病率比较差异无统计学意义。碘充足区与碘缺乏区比较,亚临床甲减、甲亢、结节性甲状腺肿的患病率差异有统计学意义(P<0.05)。碘充足区与碘缺乏区比较,尿碘水平差异有统计学意义(P<0.05),FT3、FT4、TSH差异无统计学意义(P<0.05)。结论新疆伊犁地区为碘缺乏区和碘充足区的混合地区,碘缺乏区城镇居民入院患者的尿碘水平低于碘充足区,亚临床甲减发病率高于碘充足区;碘充足区城镇居民入院患者表现为碘营养过量,甲亢和结节性甲状腺肿发病率高于碘缺乏区。
Objective To understand the urine iodine level, thyroid function status and related epidemiological characteristics of thyroid diseases in the iodine deficiency and iodine sufficient areas of Lli region. Methods The method of cluster smnpling was adopted randomly in Lli from 2008 to 2015. Research object for the permanent （ ≥5 years） above the age of 18. The epidemiological questionnaire investigation, the thyroid ultrasound examination, urine iodine level of detection and determination of thyroid function were performed. Results The prevalence of subclinical hypothyroidism, hypothyroidism, hyperthyroidism, nodular goiter hyperthyroidism were 0.38%, 2.18%, 1.53% and 0.38%, respectively. The difference of gender prevalence was statistically significant （P〈0.05）. The prevalence research of three ethnic groups （Uygur, Han, Kazakh） was found that there was statistical difference between the prevalence of the Kazak and Han ethnic （P〈0.05）, prevalence of Uighur and Han had no statistical difference. The prevalence of subclinical hypothyroidism, hyperthyroidism and nodular goiter hyperthyroidism were statistically difference between sufficient iodine area and iodine deficiency area （P〈O.05）. Sufficient iodine area compared with iodine deficiency area, the urine iodine level of sufficient iodine area was significantly higher than that of iodine deficiency area （P〈0.05）, FT3, FT4, TSH had no statistical differences （P〈0.05）. Conclusion Xinjiang Lli region is the hybrid area of iodine deficiency and iodine sufficient area, the urine iodine level of iodine deficiency urban is lower than that of iodine sufficient areas, the incidence of subclinical hypothyroidism is high. The urban residents have iodine nutrition excess Jn sufficient iodine area, the hyperthyroidism and nodular goiter are in high-risk state.
出处
《新疆医学》
2017年第6期627-629,共3页
Xinjiang Medical Journal
基金
伊犁州级课题项目(YZ201401028)
