摘要
抗苗勒管激素(anti-Müllerian hormone,AMH)是女性重要的生殖生理调节因子之一,主要由卵巢窦前卵泡及小窦状卵泡颗粒细胞分泌,不受促性腺激素的调节,能抑制卵泡的募集、选择,优势卵泡的发育。由于其血清浓度在整个月经周期中保持相对稳定,可在周期任意时刻检测,因此在多囊卵巢综合征(PCOS)、卵巢过度刺激综合征(OHSS)的诊断及治疗过程中具有重要价值;此外,对于卵巢储备功能、体外受精-胚胎移植(IVF-ET)妊娠率、卵巢肿瘤治疗效果及预后的评价也有一定的价值,为肿瘤随访提供了可靠依据。
Anti-Müllerian hormone (AMH) is one of important regulation factors of the female reproductive physiological. It is mainly secreted by the preantral follicles and small antral follicles and out-controlled by the gonadotropins (Gn), could inhibit the recruitment, chosen of follicles, and development of the advantage follicles. Because of its relatively stable serum level throughout the whole menstrual cycle and could be detected any time in the menstrual, AMH has an important value in diagnosing and treatment of polycystic ovary syndrome (PCOS) and ovarian hyperstimulation syndrome (OHSS); furthermore, it has a certain value in ovarian reserve function, pregnancy rates of in vitro fertilization embryo transfer (IVF-ET) and ovarian tumor, also provides a reliable basis for ovarian tumor’s follow-up.
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2017年第6期507-510,共4页
Chinese Journal of Reproduction and Contraception