摘要
目的:探索1979—2016年期刊文献中中医药治疗儿童变应性鼻炎的用药规律。方法:收集整理1979—2016年期刊文献中治疗儿童变应性鼻炎的中药内服复方,建立治疗儿童变应性鼻炎的中药复方数据库,利用数据挖掘技术对中医药用药规律进行分析。结果:纳入文献85篇,中药复方166首,涉及187味中药,药物使用总频次为1 885次。单味中药使用频次前5位依次是甘草、辛夷、防风、白术、黄芪;中药功效分类分析中频次前2位为发散风寒药、补气药;中药药性分类分析中温性及微温药物使用频次共计1 051次,占55.76%。另外,分别统计出2味药联用,3味药联用的使用频次,由高到低进行排序,并对其进行规则关联分析。结论:中医药治疗儿童变应性鼻炎,以使用发散风寒药和补气药为主,补散并用,药性多为温、平。
Objective：To explore the medication rules of traditional Chinese medicine（TCM） in treating allergic rhinitis in children in the periodical literatures between 1979 and 2016.Method：Periodical literatures for Chinese herbal compounds in treating allergic rhinitis in children between 1979 and 2016 were collected to build a database.Data mining technology was used to analyze the medication rules of TCM in treating allergic rhinitis in children.Result：In this study,166 Chinese herbal compounds were included,which involves187 Chinese herbs.And the total frequency of using these herbs was 1 885 times.In accordance with the frequency of using these drugs from high to low,the top five herbs were Glycyrrhizae Radix et Rhizoma,Magnoliae Flos,Saposhnikoviae Radix,Atractylodis Macrocephalae Rhizoma,and Astragali Radix.According to the classification analysis on the efficacy of TCM,the top two were wind-cold-effusing and Qi-tonifying herbs.Meanwhile,we also classified and analyzed these herbs by TCM properties,the outcome showed that the frequency of using warm herbs was 1 051 times,which accounted for 55.76%.Besides,combination rules among those herbs were observed and analyzed.Conclusion：The most commonly used herbs in treating allergic rhinitis in children are wind-coldeffusing herbs,which is followed by Qi-tonifying herbs.Meanwhile,these two herbs are often used together in the same formula.Frequently used TCM herbs are mainly warm in property.
作者
田丽
牛蔚露
许尤佳
TIAN Li NIU Wei-lu XU You-jia(The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510405, China Henan Institute of Traditional Chinese Medicine, Zhengzhou 450004, China Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510405, China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2017年第15期216-221,共6页
Chinese Journal of Experimental Traditional Medical Formulae
基金
河南省基础与前沿技术研究计划项目(162300410241)
关键词
儿童变应性鼻炎
中医药
数据挖掘
用药规律
allergic rhinitis in children
traditional Chinese medicine
data mining technology
medication rules
