摘要
目的分析国医大师徐经世教授诊治肝郁脾虚型胃脘痛的用药规律。方法收集徐经世教授诊治的肝郁脾虚型胃脘痛医案。运用结构化临床诊疗信息采集系统录入诊疗信息,通过数据挖掘技术分析诊治的常见症状、高频药物、核心药物组合等。结果本研究共搜集患者85例,157诊次,711个症状,药物103味。胃脘痛患者常见的临床症状有胃脘痛、嗳气、失眠,其中失眠的患者超过40%。出现频次超过50%的药物有竹茹、陈皮、绿萼梅、枳壳、半夏、黄连、酸枣仁。用药以甘平为主、归经以脾胃肝胆为主。复杂网络图显示竹茹、陈皮、绿萼梅、枳壳、半夏、黄连、酸枣仁、白芍为核心药物;中药药对关联规则显示竹茹→陈皮,绿萼梅→陈皮,陈皮→枳壳,绿萼梅→枳壳,绿萼梅→陈皮、竹茹,陈皮→绿萼梅、竹茹,竹茹→陈皮、绿萼梅等为药对。结论基于数据挖掘技术发现徐经世教授诊治肝郁脾虚型胃脘痛常用竹茹、陈皮、绿萼梅等药物用药以甘平为主,以肝胆脾胃为重。
Objective To analyze the medication rules of Chinese treating stomachache of stagnation of liver Qi and spleen deficiency type medicine great master Prof. XU Jingshi in Methods The medical records of Prof. XU Jingshi in treating stomachache of stagnation of liver Qi and spleen deficiency type were collected. The medical in- formation was logged by structured information collection system for clinical diagnosis and treatment. Common symp- toms, herbs of high frequency and core herb combinations were analyzed by data mining technology. Results To- tally, 85 patients were collected, 157 clinical times, 711 symptoms, 103 herbs. Common clinical symptoms of stom- achache patients were stomachache, belching and insomnia. Patients with insomnia were more than 40%. Herbs with the frequency larger than 50% were Zhuru [ Caulis Bambusae in Taenia I, Chenpi [ Pericarpium Cirri Reticulatae ], Lu＇emei [ Flos mume], Zhiqiao [ Fructus Aurantii ], Banxia [ Rhizoma Pinelliae ], Huanglian [ Rhizoma Coptidis ] and Suanzaoren [ Semen Ziziphi Spinosae ]. Herbs used were mainly mild nature and sweet flavor, and mostly in- flunced the spleen, stomach, liver and gallbladder channels. Complex network diagram showed that core herbs were Zhuru, Chenpi, Lu＇emei, Zhiqiao, Banxia, Huanglian, Suanzaoren and Baishao [Radix Paeoniae Alba]. Chinese herb group association rules showed that herb groups included Zhuru-Chenpi, Lii＇emei-Chenpi, Chenpi-Zhiqiao, Lti＇ emei-Zhiqiao, Lti＇emei-Chenpi ＆ Zhuru, Chenpi- Lu＇emei ＆ Zhuru and Zhuru-Chenpi ＆ Ly＇emei, etc. Conclusion Based on data mining technology, the authors found that when Prof. XU Jingshi treated stomachache of stagnation of liver Qi and spleen deficiency type, Zhuru, Chenpi and Lu＇emei were mostly used. Herbs used by Prof. XU were mainly mild nature and sweet flavor, and mostly influnced the spleen, stomach, liver and gallbladder channels.
作者
李艳
赵进东
忻凌
刘丽丽
侯勇
张莉
李永攀
张国梁
徐经世
LI Yan ZHAO dindong XlN Ling LIU Lili HOU Yong ZHANG Li LI Yongpan ZHANG Guoliang(First Affiliated Hospital, Anhui University of Chinese Medicine, Hefei, 230031 Third Affiliated Hospital, Anhui University of Chinese Medicine)
出处
《中医杂志》
CSCD
北大核心
2017年第15期1288-1292,共5页
Journal of Traditional Chinese Medicine
基金
国家中医药管理局徐经世国医大师传承工作室
国家自然科学基金(81603574)
安徽省自然科学基金(1708085QH213)
安徽省卫计委中医药科研课题(2016zy20)
安徽中医药大学校级科学研究基金(2016fy037)
关键词
胃脘痛
肝郁脾虚
徐经世
数据挖掘
stomachache
stagnation of liver Qi and spleen deficiency
XU Jingshi
data mining
