摘要
目的分析软组织肉瘤非计划手术后的治疗效果。方法将98例已行非计划手术的软组织肉瘤的患者作为研究对象,分为无复发组64例,复发组34例,行二次扩大切除术后,分析其复发率、转移率和患者的生存情况。结果二次手术前无复发组,术后有8例患者出现局部复发,占12.50%,4例出现淋巴结或肺转移,占6.25%,最终死亡;二次手术前复发组,术后出现局部复发的患者25例,占73.52%,伴肝或肺转移者6例,占17.65%,其中5例出现多发性转移死亡,占14.71%。两组患者复发率比较,差异有统计学意义,P<0.05,转移情况相比,差异无统计学意义,P>0.05。患者3年无病生存率数据对比,差异有统计学意义,P<0.05。结论术前正确诊断对软组织肉瘤的规范化治疗非常重要。二次手术对肿瘤的转移和患者的生存无较大的影响,但会明显降低患者的无病生存率,因此软组织肉瘤一旦确诊且为非计划性手术应尽早行二次扩大切除术治疗。
Objective To analyze the effect of non scheduled operation for soft tissue sarcoma. Methods 98 patients with soft tissue sarcoma who were not scheduled for surgery were divided into 64 cases with no recurrence and 34 cases with recurrence, after two extended resection, the recurrence rate, metastasis rate and the survival of the patients were analyzed. Results There was no recurrence in the two group before operation. 8 cases had local recurrence, accounting for 12.50%, and 4 cases had lymph node or lung metastasis, accounting for 6.25%, and finally died; In the two recurrent group, there were 25 cases with local recurrence, accounting for 73.52%, accompanied by liver or lung metastasis in 6 cases, accounting for 17.65%, including 5 cases of multiple metastasis deaths, accounting for 14.71%. The recurrence rate of the two groups was statistically significant, P〈0.05, There was no statistically significant difference in metastasis compared with P〉0.05. The data of the 3 years disease-free survival rate were statistically significant, P〈0.05. Conclusion The correct diagnosis before operation is very important for the standardized treatment of soft tissue sarcoma. The two operation had no significant effect on the metastasis of the tumor and the survival of the patients, but it significantly reduced the diseasefree survival rate, therefore, once the diagnosis of soft tissue sarcoma and non planned operation should be done as early as possible two expanded resection in the treatment.
出处
《中国继续医学教育》
2017年第16期107-109,共3页
China Continuing Medical Education
关键词
软组织肉瘤
非计划手术
术前复发
治疗效果
soft tissue sarcoma
unplanned surgery
preoperative recurrence
treatment outcome
