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氯吡格雷与低分子肝素分别治疗短暂性脑缺血发作的疗效对比 被引量:4

Analysis of Clopidogrel and Low Molecular Weight Heparin in Treatment of Transient Ischemic Attack
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摘要 目的研究分析阿司匹林联合氯吡格雷、低分子肝素治疗短暂性脑缺血发作患者的效果。方法根据2013年6月—2015年6月我院收治的82例短暂性脑缺血发作患者进行研究分析,患者的ABCD3-Ⅰ评分均低于4分,分成对照组40例,观察组42例,对照组使用阿司匹林和低分子肝素治疗,观察组使用阿司匹林和氯吡格雷治疗,对比临床治疗效果,对患者的临床治疗效果差异性进行分析研究。结果观察组治疗有效率比对照组高,结果差异存在统计学意义,P<0.05;观察组不良反应发生率和对照组比较差异无统计学意义,P>0.05,氯吡格雷和阿司匹林联合治疗的效果比阿司匹林和低分子肝素优秀。结论低危短暂性脑缺血发作患者使用阿司匹林联合氯吡格雷治疗的效果比较突出。 Objective To study the efficacy of aspirin combined with clopidogrel and low molecular weight heparin in the treatment of transient ischemic attack. Methods 82 cases of patients with transient ischemic attack from June 2013 to June 2015 in our hospital were enrolled in the study, ABCD3-I score of patients were lower than 4 points, they were divided into 40 cases in the control group and 42 cases in the observation group, the control group was treated with aspirin and low molecular weight heparin treatment, the observation group was treated with aspirin and clopidogrel treatment, the clinical treatment effect was compared and the differences of the treatment effect of patients were analyzed. Results The effective rate of the treatment group was higher than the control group, there was significant difference, P 〈 0.05; the adverse reaction rate of observation group and control group showed no significant difference, P 〉 0.05, the effect of clopidogrel and aspirin was better than aspirin and low molecular weight heparin. Conclusion Aspirin combined with clopidogrel is effective in the treatment of patients with low-risk transient ischemic attack.
作者 任广兰 张保权 REN Guanglan ZHANG Baoquan(Pharmacy Department, Daqing Hospital of Traditional Chinese Medicine, Daqing Heilongjiang 163000, China)
出处 《中国卫生标准管理》 2017年第15期80-81,共2页 China Health Standard Management
关键词 短暂性脑缺血发作 氯吡格雷 阿司匹林 低分子肝素 近期疗效 transient ischemic attack clopidogrel aspirin low molecular weight heparin short-term efficacy
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