摘要
目的:探讨不同用药方案治疗细菌性阴道炎的疗效及经济性。方法:选取2014年6月—2016年6月新余市渝水区新钢中心医院收治的细菌性阴道炎患者120例作为研究对象,以随机数字表法分为A、B、C组,每组40例。A组患者给予甲硝唑栓,B组患者给予保妇康栓,C组患者给予硝呋太尔制霉素阴道软胶囊。观察三组患者的临床疗效与不良反应发生情况,运用药物经济学方法进行成本-效果分析。结果:C组患者的总有效率明显高于A组,差异有统计学意义(P<0.05),但B组与C组、A组与B组的差异均无统计学意义(P>0.05);三组患者不良反应发生率的差异无统计学意义(P>0.05)。成本-效果分析及敏感度分析结果显示,C组方案的C/E低于B组;以A组为标准,C组方案的ΔC/ΔE低于B组。结论:根据药物经济学评价,硝呋太尔制霉素阴道软胶囊为治疗细菌性阴道炎的较佳方案。
OBJECTIVE： To probe into the efficacy and economic evaluation of different therapeutic regimens in treatment of bacterial vaginitis. METHODS ： 120 patients with bacterial vaginitis admitted into XinSteel Center Hospital from Jun. 2014 to Jun. 2016 were selected and divided into group A, group B and group C via random number table, with 40 cases in each group. Group A was treated with metronidazole suppository, group B was given Baofukang suppository, group C was treated with Nifuratel and nysfungin soft capsules. The clinical efficacy and adverse drug reactions of three groups were observed, and the cost-effectiveness analysis was carried out in pharmacoeconomics method. RESULTS ： The total effective rate of group C was significantly higher than that of group A, with statistically significant difference （P 〈 0.05） , while there were no statistical significance between group B and group C, group A and group B （ P 〉 0. 05 ） ; there was no statistical significance in incidence of adverse drug reactions among three groups （ P 〉 0.05 ）. The results of the cost-effectiveness analysis and sensitivity analysis showed that the C/E of group C was lower than group B;and take group A as standard, the AC/AE of group C was lower than group B. CONCLUSIONS： According to the pharmacoeconomics evaluation, the Nifuratel and uysfungin soft capsules is the good therapeutic regimens in treatment of bacterial vaginitis.
出处
《中国医院用药评价与分析》
2017年第7期916-918,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
细菌性阴道炎
治疗方案
经济学
Bacterial vaginitis
Therapeutic regimens
Economics
