摘要
目的探讨卵巢囊肿患者手术后创面止血方法的选择对黄体生成素(LH)、雌二醇(E2)、促卵泡素(FSH)的影响。方法选取2014年2月至2016年2月该院收治的84例卵巢囊肿患者作为研究对象,入选患者均行腹腔镜卵巢囊肿剥除术,按照囊肿创面不同处理方式分为电凝组42例和缝合组42例。电凝组采用双极电凝止血方法,缝合组采用镜下缝合止血方法。比较两组患者手术时间、术中出血量;分别于治疗前、治疗1个月、6个月检测LH、E2、FSH、卵巢间质动脉收缩期峰值速度(PSV)、窦状卵泡数目(AFC)卵巢功能状态指标,术后随访1~6个月。结果电凝组手术时间、术中出血量均明显低于缝合组,差异具有统计学意义(P<0.05);治疗后电凝组各时段FSH高于缝合组,E2、PSV、AFC显著低于缝合组,差异有统计学意义(P<0.05),而LH水平比较差异无统计学意义(P>0.05);两组患者术后随访1~6个月,电凝组发生月经紊乱、卵巢功能减退、心悸及潮热情况明显高于缝合组,差异具有统计学意义(P<0.05)。结论卵巢囊肿患者术后不同止血方式均对卵巢功能产生影响,其中电凝止血法较缝合止血法对患者影响较少,且手术时间及术中出血量相对较小。
Objective To investigate the effect of different hemostasis methods on female hormone levels,including luteinizing hormone（LH）,estradiol（E2） and follicle-stimulating hormone（FSH） and ovarian reserve function in patients with ovarian cyst. Methods A total of 84 patients with ovarian cysts were selected,which were treated with laparoscopic ovarian cystectomy in hospi- tal from February 2014 to February 2016,and were divided into the coagulation group（42 cases） and suture group（42 cases） ac- cording to the different treatment of the abscess wound. The patients of the coagulation group were treated with bipolar coagula- tion,while the patients of suture group were treated with endoscopic hemostasis. Operative time and blood loss and changes of the levels of LH, E2, FSH, peak systolic velocity（PSV） and antral follicles（AFC） of two groups were compared. Results The operative time, blood loss of the coagulation group were significantly lower than those of the suture group（P〈0.05）. After the treatment, the level of FSH of coagulation group was significantly higher than that of the suture group, while the levels of E2 ,PSV and AFC of the coagulation group were significantly lower than those of the suture group（P〈0.05）. The levels of LH between the two groups had no statistical significance（P〉0.05）. After 1- 6 months of follow-up, the incidences of menstrual disorders, ovarian dysfunction, palpitations and hot flashes of coagulation group were significantly higher than the suture group（P〈0.05）. Conclusion For the patients with ovarian cyst, coagulation method can produce a more significant effect on ovarian function than hemostasis method,as well as with relatively few operative time and blood loss.
作者
张安乐
邬小龙
张岩
杨飚
黄俊
ZHANG Anle WU Xiaolong ZHANG Yan YANG Biao HUANG Jun(Department of Gynaecology and Obstetrics ,Central Hospital of Ma＇anshan City ,Ma＇anshan ,Anhui 243000 ,Chin)
出处
《检验医学与临床》
CAS
2017年第15期2251-2253,共3页
Laboratory Medicine and Clinic
关键词
卵巢囊肿
黄体生成素
雌二醇
促卵泡素
ovarian cysts
luteinizing hormone
estradiol
follicle stimulating hormone
