摘要
目的:评价超声引导子宫肌瘤射频热消融术(ultrasound guided radiofrequency volumetric thermal ablation,URVTA)与腹腔镜子宫肌瘤切除术(laparoscopic myomectomy,LM)的临床疗效。方法:将220例患者随机分为URVTA组(n=110)与LM组(n=110)。术后3、6、12个月进行随访,评价子宫肌瘤复发情况(肌瘤数量、大小)、整体治疗效果、止痛药的使用、手术相关并发症及妊娠结局等。结果:术后URVTA、LM患者分别服用止痛药物(6.5±3.6)d与(8.7±3.8)d(P=0.83)。两组患者分别错过(12.8±6.2)与(17.2±5.9)个工作日(P=0.22),分别在(22.5±7.9)d与(28.4±7.2)d后恢复正常活动(P=0.61)。术后12个月,两组子宫肌瘤体积平均缩小87.6%与90.5%,子宫肌瘤消失率分别为94.2%(97/103)与96.2%(101/105)。2例LM患者妊娠结束后分别通过剖宫产、顺产产下健康婴儿;2例URVTA患者妊娠结束后通过顺产产下健康婴儿。结论:URVTA与LM治疗子宫肌瘤的临床疗效相似,术后12个月两种手术的患者月经出血量均下降,止痛药应用时间与并发症接近。
Objective：To evaluate the clinical effect of ultrasound guided radiofrequency volumetric thermal ablation（URVTA） and laparoscopic myomectomy（LM） for uterine fibroids.Methods：Two hundred and twenty patients were randomly divided into URVTA group（n = 110） and LM group（n = 110）.To evaluate the results of follow-up,uterine fibroids recurrence（number and size of fibroids）,the overall treatment effect,the use of analgesics,surgery related complications and pregnancy outcome were recorded in postoperative 3,6 and 12 months.Results：URVTA and LM patients took analgesic postoperatively for（6.5 ± 3.6） d and（8.7 ± 3.8） d respectively（P = 0.83）,missed（12.8 ± 6.2） and（17.2 ± 5.9） workdays（P = 0.22）,and resumed normal activities after（22.5 ±7.9） d and（28.4 ± 7.2） d（P = 0.61） respectively.In 12 months after the operation,the average size of uterine fibroids in the two groups were reduced 87.6%（URVTA） and 90.5%（LM）,and 94.2%（97/103 cases,URVTA） and 96.2%（101/105 cases,LM）fibroids disappeared.Two LM patients were pregnant with one cesarean delivery and one vaginal delivery of healthy infant.Two pregnancies in the URVTA group both ended in full-term vaginal delivery of healthy infant.Conclusions：The clinical efficacy of URVTA and LM is similar in the treatment of uterine fibroid,after 12 months,the volume of menstrual blood are both decreased in the two groups,the duration of taking analgesic and the incidence of complications are similar.
出处
《腹腔镜外科杂志》
2017年第6期463-467,共5页
Journal of Laparoscopic Surgery
关键词
子宫肌瘤
射频热消融术
腹腔镜检查
超声引导
Uterine fibroid
Radiofrequency volumetric thermal ablation
Laparoscopy
Ultrasound guidance
