摘要
成纤维细胞生长因子(Fibroblast growth factor,FGF)家族在个体的胚胎发育、卵泡发育、生殖细胞的成熟、能量代谢、器官的发育和形成、组织修复、骨骼发育以及内环境的稳定等多种生物学过程中发挥重要作用。成纤维细胞生长因子家族根据其作用方式分为旁分泌型成纤维细胞生长因子、自分泌型成纤维细胞生长因子和内分泌型成纤维细胞生长因子。各家族的功能各不相同又有所交叉,目前关于该家族的研究主要集中于胚胎发育、动物繁殖以及糖脂代谢等方面。本文主要对哺乳动物卵巢发育过程中成纤维细胞生长因子的研究进行综述,以深入探索卵巢发育的调控机制。
The fibroblast growth factor family plays the important role in a variety of biological processes including embryonic development, follicular development, maturation of the germ cells, energy metabolism, organ formation and development, tissue regeneration, skeletal development and homeostasis, and so on. The FGF family was divided into paracrine FGFs, autocrine FGFs and endocrine FGFs depending on its different modes of action. The functions of FGFs are different while some are overlapped. Now, the researches of FGFs are mainly focused on embryonic development, animal reproduction and glycolipid metabolism. Here the biological functions of FGFs in mammalian ovary development are reviewed, in order to further explore the regulatory mechanism of ovary development.
出处
《畜牧兽医学报》
CAS
CSCD
北大核心
2017年第8期1373-1380,共8页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
国家自然科学基金项目(31472078
31402041
31572371
31501941
31501926)
国家肉羊产业技术体系专项(CARS-39)
中央级公益性科研院所基本科研业务费专项(2013ywf-zd-1
2015ywf-zd-2
2015ywf-zd-8)
中国农业科学院科技创新工程(ASTIP-IAS13)
内蒙古自治区科技重大专项
内蒙古自治区战略性新兴产业发展专项资金计划
宁夏农林科学院科技创新先导资金项目(DWJLC-2016001)
