摘要
近年来,由禽致病性大肠杆菌(avian pathogenic Escherichia coli,APEC)引起的禽大肠杆菌病给全球的养禽行业造成了重大的经济损失,并且APEC引起的禽大肠杆菌病在中国是最主要的家禽细菌病。越来越多的证据显示,APEC是人源尿路感染大肠杆菌(uropathogenic Escherichia coli,UPEC)和致脑膜炎大肠杆菌(neonatal meningitis Escherichia coli,NMEC)的毒力基因储藏库,甚至可能会直接导致两种疾病的发生。因此,如何有效地控制APEC不仅是一个紧迫的问题,更是一个巨大的挑战。对APEC的分离鉴定、流行病学特征、药物敏感性等内容的研究对APEC引起的禽大肠杆菌病的控制具有指导意义。为了更好地防控大肠杆菌病,文章主要从临床症状、病理变化、毒力因子、致病机理和诊断方法几个方面对鸭致病性大肠杆菌进行了综述,以期为进一步研究提供参考。
In recent years, avian pathogenic Escherichia coli （ APEC ） were responsible for avian colibacillosis and caused significant economic losses in the poultry industry worldwide. Avian colibacillosis caused by APEC was the predominant bacterial disease of poultry in China. Mount- ing evidence had revealed that APEC caused UPEC and NMEC in human beings as a vehicle or even a reservoir. Therefore, the effective meas- ures of APEC control had become an urgent issue, also a great challenge. The isolation and identification of APEC, analysis of molecular epide- mialogical characteristic, sensitivity test played an important role in controlling avian colibacillosis. For better control and prevention of the avi- an pathogenic Escherichia coli, the article summarized the clinical symptoms, pathological changes, virulence factors, pathogenesis and diagno- sis to provide further research reference.
出处
《黑龙江畜牧兽医》
CAS
北大核心
2017年第8期72-77,共6页
Heilongjiang Animal Science And veterinary Medicine
基金
"十二五"国家科技支撑计划项目(2015BAI07B02-02)
关键词
鸭
大肠杆菌病
毒力因子
致病机理
诊断方法
duck
colibaeillosis
virulence factors
pathogenic mechanism
diagnostic methods
