摘要
目的:探讨分析胺碘酮与美托洛尔联合应用于治疗慢性心力衰竭(CHF)合并室性心律失常(VA)的临床效果。方法:选取笔者所在医院74例CHF合并VA患者,按随机数表法将其分为对照组与试验组,每组37例,对照组单纯采用美托洛尔治疗,试验组采用胺碘酮+美托洛尔联合治疗,比较两组临床疗效。结果:试验组心功能改善及心律失常总有效率均显著优于对照组(P<0.05);两组药物不良反应率比较,差异无统计学意义(P>0.05);随访1年,试验组心血管事件发生率为5.41%,明显低于对照组的16.22%(P<0.05)。结论:采用胺碘酮+美托洛尔治疗慢性心力衰竭合并室性心律失常效果确切,且不良反应少,值得推荐使用。
Objective： To investigate the effect of Amiodarone combined with Metoprolol in the treatment of CHF complicated with VA.Method： 74 patients with CHF complicated with VA were randomly divided into the control group（n=37, treated with metoprolal） and the experimental group（n=37, treated with amiedarone and metoprolol）, the effect in two groups was compared.Result： The improvement of cardiac function and the total effective rate of arrhythmia in the experimental group were significantly better than those in the control gronp（P〈0.05）.The adverse drug reaction in two group had no significal difference（P〉0.05）.The incidence of cardiovascular events in the experimental group was 5.41%, it was lower than 16.22% in the control group follow up 1 year（P〈0.05）.Conclusion： The effect of Amiedarone combined with Metoprolol in the treatment of CHF complicated with VA is significant, and less adverse reactions.
作者
蔡家庆
CAI Jia-qing(HejiangCountyPeople＇sHospitai, Hejiang646200, Chin)
出处
《中外医学研究》
2017年第23期1-3,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
