摘要
目的探讨柴胡注射液致过敏性休克的规件和特点，为临床合理用药提供参考。方法检索1996-2015年国内医药数据昨，收集柴胡注射液敛过敏性休克病例报告，进行统计和分析。结果共检索到柴圳注射液敛过敏性休兜18侧，男女相当，均为肌内注射给药；13例（72．2％）发生在用药后的5min以内，临床农现以心血管系统和中枢神经系统为主。经积极的抗休克治疗，17例恢复正常，1例死亡。结论柴胡注射液敛过敏性休克临味时有发生，临床用药须晕视过敏史询问、用药过程中不良反应的观察，减少用药安全隐患。
Objective To investigate the clinic features and regularity of anaphylactic shock induced by puplearum injection,and to provide reterence in clinic for rational use of bupleurum injection. Methods Checked out the case reports of ansphviactic shock induced by bupleucum injection in the data- bases in China from 1996 to 2015 for slatistics and analysis. Results 18 cases of anaphylactic shock were reported and sexual equality,and all were injected intramuscularly;13 cases（72. 2% ） occurred within 5min and cardiovascular system and central nerwms system as the main clinical manifestations. By the active anti - shock therapy, 17 cases recovered and 1 ease died. Conclusion Allergie shock induced by bupleurum injection happens now and then in clinics,so clinical drug using shonld pay attention to the history, of allergies and medication adverse reactions in the process of observation,in order to reduce drug safety hazards.
出处
《中国基层医药》
CAS
2017年第18期2776-2779,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
过敏反应
休克
柴胡注射液
回顾性研究
Anaphylaxis
Shock
Bupleurum Injection
Retrospective Studies
