摘要
目的分析首剂用药初始缓慢滴注与药物不良反应的相关性。方法以2016年1—6月的321例患者为观察组,另外选择2015年6—12月的315例患者为对照组,两组患者分别采用不同的治疗方式,对照组采用常规输液方式治疗,观察组采用首剂用药初始缓慢滴注方式治疗,对比两组不良反应发生率及严重程度。结果两组患者的不良反应发生率比较,差异无统计学意义(P>0.05);但观察组患者的重度不良反应发生率(1.6%)低于对照组(3.5%),差异有统计学意义(P<0.05)。结论首剂用药初始缓慢滴注能够有效降低药物引发的不良反应严重程度,提升治疗安全性。
Objective To analyze the correlation between initial slow infusion and adverse drug reactions. Methods 321 cases from January to June 2016 were selected as observation group, another 315 cases from June to December 2015 were selected as control group, two groups were treated with different treatment methods, the control group using conventional infusion therapy, the observation group with initial treatment of the first dose of slow infusion, two groups of adverse reaction rate and severity were compared. Results There was no significant difference in the incidence of adverse reactions between the two groups（P 〉 0.05）,but the incidence of severe adverse reactions in the observation group （1.6%） was significantly lower than that in the control group （3.5%）, and the difference was statistically significant （P 〈 0.05）. Conclusion The initial slow infusion of the first dose can effectively reduce the severity of drug induced adverse reactions and improve the safety of treatment.
出处
《中国卫生标准管理》
2017年第17期81-83,共3页
China Health Standard Management
关键词
首剂用药
缓慢滴注
药物不良反应
the first drug
slow infusion
adverse drug reactions
