摘要
血管周围间隙(PVS)可以存在于所有人群中,但其大小和数量随年龄的增长而增加。目前对PVS的认识主要是通过磁共振成像(MRI)进行,在一些情况下PVS会扩张,即为PVS扩大(EPVS)。在MRI上EPVS常与腔隙性梗死(LI)、白质疏松(LA)等脑小血管病共存,尤其与LI鉴别困难,导致EPVS对脑组织造成的损害被LI、LA等掩盖,长期以来被视为良性改变。然而,越来越多的证据显示EPVS与认知功能障碍有一定关系,与脑出血、LI及大动脉粥样脑梗死等脑血管病相关,是脑小血管病的一种类型。
Perivascular space （PVS） can exist in all populations, but its size and number increase with age. At present, PVS is mainly known through magnetic resonance imaging（MRI） method. In some situation, PVS will expand,which is called enlarged PVS （EPVS）. EPVS often coexists with lacunar infarction （ LI）, leukoarai （LA） and other cerebrovascular disease on MRI,and it is especially difficult to identify with LI, resulting that LI and LA cover the brain tissue damage caused by EPVS which is deemed as benign alteration. However,there is growing evidence showing that EPVS is associated with cognitive dysfunction and cerebrovascular disease such as cerebral hemorrhage, LI and atherosclerotic cerebral infarc- tion,which is a type of smalt brain vascular disease.
出处
《医学综述》
2017年第15期2938-2942,共5页
Medical Recapitulate
关键词
血管周围间隙扩大
磁共振成像
脑小血管病
认知功能
Enlarged perivascular space
Magnetic resonance imaging
Small brain vascular disease
Cognitive func- tion
