摘要
缺血再灌注损伤无复流指局部缺血组织重新恢复血流后,缺血区反而不能得到充分血液灌注的现象,严重影响心肌梗死患者的预后。该病主要与内皮细胞损伤有关,目前尚缺乏有效的治疗办法。中医药可从多层面、多途径、多靶点治疗该病。初步分析了缺血再灌注损伤无复流现象的患病因素以及基本病机,并对从脾论治进行了深入探讨,为临床应用和基础研究提供理论依据。
Coronary no-reflow phenomenon after ischemia-reperfusion injury is the phenomenon that local ischemic tissue fails to be filled with blood fully after blood supply recovered. This disease seriously affects the prognosis of acute myocardial infarction patients. It is concerned with the injury of endothelial cells. However,there is no effective treatment methods. Traditional Chinese medicine can treat this disease through multiple levels,approaches and targets. This paper analyzes the basic pathogenesis and factors of no-reflow preliminarily and explored deeply treatment through spleen to providing some references for clinical application and theoretical research.
出处
《山东中医杂志》
2017年第8期635-637,641,共4页
Shandong Journal of Traditional Chinese Medicine
基金
天津中医药大学中西医结合学院研究生创新基金(编号:ZXYCX201502)
国家自然科学基金青年基金(编号:81503504)
天津市卫计委科技基金攻关项目(编号:2015KG110)
关键词
缺血再灌注损伤
无复流现象
病机
从脾论治
ischemia-reperfusion injury
no-reflow phenomenon
etiology
treatment from spleen
