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糖调节受损时胰岛B细胞功能的改变 被引量:1

The change of B-cell function in patients with impaired glucose regulation
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摘要 评估胰岛B细胞功能的方法有很多,如:胰岛素钳夹技术、微小模型技术、基础状态法、胰岛素耐量试验、口服葡萄糖耐量试验(OGTT)等,它们各有优缺点。糖调节受损(IGR)包含3种表现形式,即:空腹血糖受损(IFG),糖耐量低减(IGT),IFG、IGT二者兼有状态(IFG+IGT)。国内外研究显示不同糖代谢状态下胰岛素抵抗和胰岛素分泌功能的变化不尽相同。本研究对糖调节受损时胰岛B细胞功能的改变做一综述。 There are many methods to assessment the functionof B-cell, such as Clamp, MMT, Basical Status, ITr, OGTT and so on. They have their own merit and shortcoming. Impaired glucose regulation (IGR) include three forms: impaired fasting glucose; impaired glucose tolerance; impaired fasting glucose and impaired glucose tolerance. It was reported that the characteristics of insulin resistance and B-cell secretion were very differently in patients with impaired glucose metabolism in domestic and international studies. In this paper, the change of B-cell function in patients with impaired glucose regulation were reviewed.
作者 董智慧
出处 《疾病监测与控制》 2017年第8期633-634,共2页 Journal of Diseases Monitor and Control
关键词 胰岛B细胞功能 胰岛素抵抗 胰岛素敏感性 糖调节受损 B-cell function insulin resistance insulin sonsitivity impaired glucose regulation
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