摘要
目的:探究与分析子宫内膜异位症与血清、腹腔液中CA125、TNF-α的相关性。方法:本次研究选取2015-06-2016-06收治的子宫内膜异位症患者60例为观察组,另选取同期健康体检女性60例为对照组,同时将观察组患者按照不同时期分为Ⅰ期14例,Ⅱ期14例,Ⅲ期17例,Ⅳ期15例,观察与分析血清及腹腔镜液中CA125、TNF-α水平与子宫内膜异位症发生、发展的关系。结果:观察组血清CA125、TNF-α水平及腹腔液中CA125、TNF-α水平较对照组高,差异有统计学意义(P<0.05)。Ⅲ期与Ⅳ期组与Ⅰ期与Ⅱ期组相比血清CA125、TNF-α水平及腹腔液中CA125、TNF-α水平均较高,差异有统计学意义(P<0.05)。结论:子宫内膜异位症血清与腹腔液中CA125、TNF-α水平要明显高于健康妇女,二者的水平与疾病发生、发展具有密切关系,有利于临床工作中对子宫内膜异位症的诊断。
Objective：To discuss and analyze the correlation between endometriosis and CA125,TNF alpha levels in serum,peritoneal fluid.Method：Sixty patients with endometriosis from June 2015 to June 2016 were selected as observation group,60 women from the healthy check-up at the same time were as control group.According to the different period,the patients were divided into stageⅠ of 14 cases,stageⅡ of 14 cases,stageⅢ of 17 cases and stageⅣ of 15 cases.The relationship between CA125,TNF alpha levels in serum and laparoscopic liquid and the incidence and development of endometriosis was observed and analyzed.Result：CA125,TNF alpha levels in serum and peritoneal fluid of the observation group were higher than those of the control group,and the difference was statistically significant（P〈0.05）.CA125,TNF alpha levels in serum and peritoneal fluid of stageⅢ and stageⅠgroup were higher than those of stageⅣ group and stageⅡ group,respectively,and the differences were statistically significant（P〈0.05）.Conclusion：CA125,TNF alpha levels in serum and peritoneal fluid of endometriosis patients were significantly higher than those of healthy women.The levels of CA125 and TNF alpha might have a close relationship with disease development and would be helpful to the clinical diagnosis of endometriosis.
出处
《临床血液学杂志（输血与检验）》
CAS
2017年第4期625-627,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
