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重症肝炎并发医院感染的危险因素分析 被引量:3

Risk Factors of Nosocomial Infection in Patients With Severe Hepatitis
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摘要 目的分析重症肝炎并发医院感染的相关因素及危险因素。方法回顾分析我院在2013年7月—2016年8月收治重症肝炎并发医院感染患者279例,分析主要内容包括感染部位、菌种、性别、年龄、侵入性操作、抗菌药物的应用等情况。结果重症肝炎并发医院感染患者65例,占23.3%,其中主要发生感染的部位:腹部28例,占43.1%;下呼吸道14例,占21.5%;上呼吸道11例,占16.9%。引发医院感染的主要菌种有革兰阳性球菌共11株,占26.8%;肺炎克雷伯菌共8株,占19.5%;大肠埃希菌7株,占17.1%。重症肝炎患者并发医院感染中性别、年龄、侵入性操作、滥用抗生素情况为主要危险因素(P<0.05)。结论在临床治疗中应当注意患者的消毒隔离,遵守无菌操作规范,增强抗生素用药规范。 Objective To analyze the related factors and risk factors of nosocomial infection in severe hepatitis. Methods 279 cases of severe hepatitis complicated with nosocomial infection in our hospital from July 2013 to August 2016 were analyzed retrospectively, main contents included infection site, bacteria, gender, age, invasive operation and application ofantibiotics. Results There were 65 cases of severe hepatitis complicated with nosocomial infection, accounting for 23.3%, among them, the main location of infection: abdominal 28 cases, accounting for 43.1%; lower respiratory tract 14 cases, accounting for 21.5%; upper respiratory tract in 11 cases, accounting for 16.9%. There were 11 strains of gram positive cocci in the hospital infection, accounting for 26.8%. A total of 8 strains of klebsiella pneumoniae, accounting for 19.5%; Escherichia coli was 7 cases, accounting for 17.1%. The gemder, age, invasive operation and abuse of antibiotics were the major risk factors of nosocomial infection in patients with severe hepatitis(P〈0.05). Conclusion In clinical treatment, attention should be paid to the disinfection and isolation of patients, to observe the aseptic operation standard, and to strengthen the standard of antibiotic use.
出处 《中国继续医学教育》 2017年第18期98-100,共3页 China Continuing Medical Education
关键词 重症肝炎 新生儿缺氧缺血性脑病 疗效观察 severe hepatitis neonatal hypoxic-ischemic encephalopathy curative effect observation
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