摘要
目的比较脑梗死合并高同型半胱氨酸血症(HHcy)型高血压(H型高血压)及原发性高血压患者脑血管病变特点。方法检测258例脑梗死合并高血压患者的同型半胱氨酸(Hcy)水平,根据Hcy水平分为H型高血压组及高血压组。采用DSA检查患者的脑血管病变情况。结果 H型高血压组112例,高血压组146例。两组间性别、年龄、收缩压、舒张压,以及吸烟、饮酒史比率差异均无统计学意义(均P>0.05)。两组均以颈内动脉(ICA)及大脑中动脉(MCA)受累多,以颅内血管狭窄病变为主。与高血压组比较,H型高血压组颅内血管病变及重度脑血管狭窄发生率显著增高,侧支循环比率显著降低(均P<0.05)。结论脑梗死合并H型高血压患者血管狭窄较多,程度较重,且侧支代偿较少。
Objective To compared the characteristics of cerebrovascular pathological changes in cerebral infarction patients accompanied with hyperhomocysteinemia（ HHcy） and primary hypertension. Methods The level of homocysteine（ Hcy） of 258 cerebral infarction patients with primary hypertension were detected,and patients were divided into H type hypertension group and hypertension group according to the level of Hcy. The cerebrovascular pathological changes were observed by DSA. Results There were 112 cases in H type hypertension group,and 146 cases in hypertension group. There had no significant difference between the two groups in gender,age,systolic pressure,diastolic pressure,and the rates of drinking and smoking（ all P 0. 05）. Internal carotid artery（ ICA）and middle cerebral artery（ MCA） were involvements,and it was mainly with intracranial artery stenosis in the two groups. Compared with hypertension group,the rates of intracranial vessel lesion and severe cerebrovascular stenosis in H type hypertension group were significantly increased,and the rate of collateral vessels was significantly decreased（ all P 0. 05）. Conclusion The stenosis of cerebrovascular seems much more narrower,heavier,and have less collateral circulation in cerebral infarction patients with H type hypertension.
出处
《临床神经病学杂志》
北大核心
2017年第4期278-280,共3页
Journal of Clinical Neurology
关键词
H型高血压
脑血管造影
脑梗死
hyperhomocysteinemia with hypertension
digital subtractiona angiography
cerebral infarction
