摘要
目的探讨未成熟血小板相关参数在幼儿缺铁性贫血(IDA)疾病中临床应用价值。方法采用XE-5000全自动血液分析仪检测温州地区63例健康幼儿外周血中未成熟血小板绝对值(IPF)、未成熟血小板比率、高荧光未成熟血小板比率、血小板平均侧向荧光强度(PLT-X)及网织血小板计数(PLT-O)。同期测定146例临床确诊的儿童IDA患者外周血的相同参数按贫血的严重程度划分,与对照组进行比较并做统计学分析。结果对照组PLT-、未成熟血小板比率、高荧光未成熟血小板比率、IPF、PLT-X参数男女之间差异均无统计学意义(P>0.05)。儿童IDA患者检测指标IPF、未成熟血小板比率、高荧光未成熟血小板比率及PLT-X指标与对照组比较,差异有统计学意义(P<0.01)。轻度IDA、中度IDA患者PLT-O指标与对照组比较,差异有统计学意义(P<0.01)。结论提示PLT相关新参数在IPF相关参数对临床IDA患者早期诊断和治疗有一定的价值。
Objective To discuss the clinical value of immature platelet fraction（ IPF） related parameters in diagnosis of children with iron deficiency anemia（ IDA）. Methods 63 peripheral blood samples were collected from healthy children in Wenzhou. Sysmex XE-5000 was used to detected five IPF related parameters including absolute value of immature platelet（ IPF）,ratio of immature platelet,ratio of high fluorescence immature platelet,average intensity of lateral fluorescence of platelet（ PLT-X） and number of reticular platelet（ PLT-O）. Meanwhile,146 peripheral blood samples collected from children clinically diagnosed IDA were detected. IDA patients were classified according to the severity of the anemia,and compared them with healthy children. Statistical analysis was performed to the data. Results In control group,these parameters of PLT-,immature platelet ratio,high fluorescence immature platelet ratio,and IPF,PLT-X parameters showed no statistical significance on the difference between male and female（ P〈0. 05）. Compared with the control group,the IPF,immature platelet ratio,high fluorescence,immature platelet ratio,and PLT-X index in children with IDA showed statistical significance on the difference（ P〈0. 01）. Mild IDA,moderate IDA patients,PLT-O index were compared with those in the control group,and the difference was statistically significant（ P〈0. 01）. Conclusion The results showed that these new IPF related parameters presented some value in clinical diagnosis of children with IDA.
出处
《中国卫生检验杂志》
CAS
2017年第16期2343-2345,共3页
Chinese Journal of Health Laboratory Technology
关键词
未成熟血小板
缺铁性贫血
幼儿
Immature platelet fraction
Iron deficiency anemia
Children
