摘要
目的观察参麦注射液对慢性肺源性心脏病患者血流功能状况指标的影响。方法将本院2014年1月~2015年11月呼吸内科自愿参加试验的慢性肺源性心脏病患者124例随机分为对照组和实验组。62例对照组给予控制感染、强心、利尿、平喘祛痰、持续低流量吸氧、纠正电解质及酸碱平衡紊乱等常规西医治疗,62例实验组在对照组治疗的基础上,合用参麦注射液,疗程为14 d。两组在治疗前后分别进行血流功能状况指标(血液流变学指标、血细胞比容和纤维蛋白原)测定。结果治疗后,对照组和实验组的全血高切还原黏度[(7.86±1.28)、(7.71±1.11)m Pa·s]、全血低切还原黏度[(54.96±9.43)、(49.00±4.51)m Pa·s]、血浆黏度[(1.88±0.28)、(1.43±0.18)m Pa·s]、纤维蛋白原[(2.50±1.11)、(2.05±1.13)g/L]、血细胞比容[(0.45±0.09)、(0.43±0.04)L/L]与治疗前比较均有所改善(P<0.05)。治疗后,实验组的各指标(除全血高切还原黏度外)好转改善程度明显优于对照组(P<0.05)。结论在常规西医治疗的基础上加用参麦注射液治疗慢性肺源性心脏病,可明显改善患者的血流功能状况,可能对患者病情的长期稳定控制,减少并发症的发生具有积极意义。
Objective To observe the influence of Shenmai Injection on blood flow function in patients with chronic pulmonary heart disease.Methods 124 patients（volunteers） with chronic pulmonary heart disease treated in department of clinical laboratory of our hospital from January 2014 to November 2015 were randomly divided into control group and experimental group.62 cases of control group were treated with conventional western medicine treatment such as control infection,strong heart,diuretic,smooth wheezing expectorant,low flow oxygen,correct electrolyte and acid-base balance disorder and so on.The experimental group（n=62） was treated with conventional western medicine combined Shenmai Injection.The course of the treatment were 14 days.Blood flow function indexes（blood rheology,haematocrit and fibrinogen） were determined before and after treatment in two groups.Results After treatment,the whole blood high shear reductive viscosity [（7.86±1.28）,（7.71±1.11） m Pa·s] whole blood low shear reduction viscosity [（54.96±9.43）,（49.00±4.51） m Pa·s],plasma viscosity [（1.88±0.28）,（1.43 ±0.18） m Pa·s],fibrinogen [（2.50 ±1.11）,（2.05 ±1.13） g/L] and hematocrit [（0.45 ±0.09）,（0.43±0.04） L/L] in control group and experimental group were improved compared with before treatmenrt（P〈0.05）.The treatment group showed the improved significantly better than the control group except the whole blood high shear reductive viscosity（P 0.05）. Conclusion On the basis of conventional western medicine treatment,Shenmai Injection added treating chronic pulmonary heart disease can obviously improve blood flow function indexes of patients,and it may be has an positive meaning for long term stablely control of patients′ condition and reduce the occurrence of complications.
出处
《中国当代医药》
2017年第24期109-111,共3页
China Modern Medicine
