摘要
目的研究4种临床方法用于促宫颈成熟的实用性和安全性。方法选取2016年于崇州市妇幼保健院产科确诊为宫颈不成熟的足月产妇100例,用电脑软件随机分为4组,每组25例,分别采用宫颈扩张水囊、缩宫素、地诺前列酮栓、米索前列醇4种不同方法处置,待宫颈成熟时进行引产。比较4组产妇在处置前和处置后1 d的Bishop得分情况、引产耗时、分娩情况及产后母婴情况。结果在Bishop得分方面,处置后得分宫颈扩张水囊组高于其他3组(P<0.05),地诺前列酮栓组和米索前列醇组高于缩宫素组(P<0.05)。处置至临产耗时地诺前列酮栓组和米索前列醇组低于其他两组(P<0.05)。阴道分娩率宫颈扩张水囊组和地诺前列酮栓组差异无统计学意义(P>0.05),但高于其他两组(P<0.05)。宫缩强度米索前列醇组高于其他3组(P<0.05)。结论宫颈扩张水囊、地诺前列酮栓及米索前列醇均有良好的改善宫颈成熟的效果,其中宫颈扩张水囊安全性更好,不良反应少,值得临床推广。
Objective To explore the applicability and safety of four different methods for cervical ripening in clinical practice. Methods 100 full - term puerperas diagnosed of cervical immature in Chongzhou Maternal and Child Healthcare Hospital in 2016 were selected. They were randomly divided into four groups by computer, each with 25 cases. Four groups were treated by cervical dilatation of water sac, oxytocin, dinoprofen suppository and misoprostol respectively, when the cervix was ripe, induced labor. The Bishop score, labor induction time, delivery status and postnatal maternal and neonatal status were compared between the four groups before and 1 day after treatment. Results The Bishop score was significantly higher in the cervical dilation balloon group than the other three groups （ P 〈 0. 05 ）. The scores of the dinoprostone group and the misoprostol group were significantly higher than the oxytocin group （ P 〈 0. 05 ）. The time from disposal to labor of dinoprostone suppositories group and misoprostol suppository group were significantly lower than the other two groups（ P 〈 0. 05 ）. The vaginal delivery rate of cervical dilatation balloon group and dinoprostone group was not significantly different from each other, and was significantly higher than oxytocin group and misoprostol group （ P 〈 0. 05 ）. Misoprostol group had higher proportion of contraction intensity than the other three groups （ P 〈 0. 05 ）. Conclusion Cervical dilation balloon, dinoroprostone suppository and misoprostol have a good effect on improving cervical ripening. Cervical dilatation balloon is more safe and with less adverse reactions, thus is worthy of clinical promotion.
出处
《中国计划生育和妇产科》
2017年第9期44-47,共4页
Chinese Journal of Family Planning & Gynecotokology
