摘要
目的 评价复合丙泊酚时羟考酮用于小儿无痛胃镜术的效果.方法 择期行无痛胃镜术患儿60例,性别不限,年龄2-7岁,体重10- 28 kg,ASA分级Ⅰ或Ⅱ级,采用随机数字表法,将其分为2组（n=30）：羟考酮组（O组）和舒芬太尼组（F组）.患儿由家属抱入胃镜室,静脉注射丙泊酚1.5-2.0 mg/kg和盐酸戊乙奎醚0.3 mg,O组静脉注射羟考酮0.1 mg/kg,F组静脉注射舒芬太尼0.1μg/kg.术中出现体动反应时,静脉追加丙泊酚1.0 mg/kg.记录患儿术中体动、喉痉挛及呼吸抑制等不良反应的发生情况;记录患儿术后呕吐及疼痛等的发生情况.结果 与F组比较,O组术中体动、喉痉挛、呼吸抑制及术后疼痛的发生率降低（P〈0.05）.结论 复合丙泊酚时羟考酮用于小儿无痛胃镜术的效果优于舒芬太尼.
Objective To evaluate the efficacy of oxycodone for painless gastroscopy in pediatric patients when combined with propofol.Methods Sixty pediatric patients of either sex,aged 2-7 yr,weighing 10-28 kg,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,scheduled for elective painless gastroscopy,were divided into 2 groups （n=30 each） using a random number table：oxycodone group （O group） and sufentanil group （F group）.The pediatric patients held by their parents entered the gastroscopy room,and propofol 1.5-2.0 mg/kg and penehyclidine hydrochloride 0.3 mg were intravenously injected.Oxycodone 0.1 mg/kg and sufentanil 0.1 μg/kg were intravenously injected in O and F groups,respectively.When body movement occurred during operation,additional propofol 1.0 mg/kg was intravenously injected.The occurrence of adverse reactions such as intraoperative body movement,laryngospasm and respiratory depression was recorded.The occurrence of postoperative vomiting and pain （FLACC pain scale scores 〉3） was also recorded.Results The incidence of intraoperative body movement,laryngospasm and respiratory depression and postoperative pain was significantly lower in O group than in F group （P〈0.05）.Conclusion When combined with propofol,oxycodone produces better efficacy than sufentanil for painless gastroscopy in pediatric patients.
出处
《中华麻醉学杂志》
CSCD
北大核心
2017年第7期804-806,共3页
Chinese Journal of Anesthesiology
