摘要
目的:探讨无创呼吸机对COPD并发呼吸衰竭PaCO_2、SpO_2的影响。方法:将122例COPD并发II型呼吸衰竭患者随机分为两组,在常规治疗基础上,观察组61例采用吸氧联合无创呼吸机治疗,对照组61例仅采用低流量吸氧治疗。比较两组患者的临床疗效及治疗前后PaO_2、PaCO_2、SpO_2、RR、HR,治疗后不良反应发生情况。结果:观察组患者总有效率为80.3%,显著高于对照组的63.9%(P<0.05)。治疗后观察组患者PaO_2、PaCO_2、SpO_2均显著优于对照组(P<0.05)。治疗后观察组患者RR、HR均显著低于对照组(P<0.05)。两组患者在治疗过程中的不良反应发生情况差异无统计学意义(P>0.05)。结论:无创呼吸机可有效改善COPD伴II型呼吸衰竭患者PaO_2、PaCO_2、SpO_2指标,可迅速缓解患者的呼吸困难,不良反应少。
Objective：To investigate the effect of noninvasive ventilation on PaCO2, SpO2 changes and adverse reactions of COPD with respiratory failure.Methods：122 patients with COPD and II respiratory failure were selected.All patients were randomly divided into observation group and control group, each group got 61 cases.The clinical efficacy, PaO2, PaCO2, SpO2, RR, HR before and after treatment, and adverse reactions after treatment of the two groups were compared.Results：The total effective rate of the observation group （80.3%） was significantly higher than that of the control group （63.9%）（P〈0.05）.After treatment, the PaO2, PaCO2, SpO2 in the observation group were significantly better than those in the control group （P〈 0.05）.After treatment, the RR and HR in the observation group were significantly lower than those in the control group （P 〈 0.05）.There was no significant difference in adverse reactions between the two groups （P〉0.05）.Conclusion：Noninvasive ventilator can effectively improve PaO2, PaCO2, SpO2 in patients with COPD accompanied with respiratory failure of II, relieve symptoms of dyspnea, less adverse reactions.
出处
《陕西医学杂志》
CAS
2017年第9期1217-1218,1232,共3页
Shaanxi Medical Journal
关键词
肺疾病
慢性阻塞性/并发症
呼吸功能不全/病因学
呼吸功能不全/治疗
通气机
负压
Pulmonary disease,chronic obstructive/complications
Respiratory insufficiency/etiology
Respiratory insufficiency/therapy
Ventilator,negative pressure
