摘要
目的探讨创伤性癫痫患者血浆前清蛋白水平与患者自我效能、生活质量及临床预后的关系。方法选取2015年8月至2016年4月在该院治疗的颅脑外伤患者120例作为研究对象,根据患者是否发生癫痫,分为对照组和观察组,对比两组患者血浆前清蛋白、自我效能、生活质量评分,采用相关性分析探讨血浆前清蛋白水平与患者自我效能、生活质量及临床预后的关系,采用Logisitic回归分析探讨创伤性癫痫患者预后不良的风险因素。结果观察组创伤(CRAMS)评分、血浆前清蛋白、自我效能、生活能力低于对照组患者,差异有统计学意义(P<0.05)。Pearson相关性分析发现,血浆前清蛋白与CRAMS评分、自我效能、生活能力呈正相关(r=0.78、0.65、0.89,P<0.05)。Logistic回归分析结果提示CRAMS下降0.2分(P=0.015)、血浆前清蛋白下降5μg/L(P=0.032)均是脑创伤性癫痫患者预后的独立风险因素。结论血浆前清蛋白水平和CRAMS评分是创伤性癫痫患者死亡的独立风险因素,对于颅脑损伤的患者应注意检测血浆前清蛋白水平。
Objective To study the relationship between the level of plasma pre-albumin and the patients′self efficacy,quality of life and prognosis in patients with traumatic epilepsy.Methods Totally 120 cases of patients with craniocerebral trauma treated in our hospital from August 2015 to April 2016 divided into control group and observation group,according to whether patients with epilepsy,compared plasma albumin,self efficacy,quality of life score of the two groups,correlation analysis were used to investigate the relationship between plasma albumin level and self efficacy in patients with quality of life and clinical prognosis,logisitic regression analysis was used to study the risk factors of traumatic epilepsy in patients with poor prognosis.Results The CRAMS score,plasma pre-albumin,self-efficacy and life ability of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).Pearson correlation analysis showed that plasma pre-albumin was positively correlated with CRAMS score,self-efficacy and life ability(r=0.78,0.65,0.89,P<0.05).Logistic regression analysis showed that CRAMS decreased 0.2points(P=0.015),plasma albumin decreased by 5g/L(P=0.032)was an independent risk factor for prognosis of patients with traumatic epilepsy.Conclusion Plasma level of pre-albumin and CRAMS score are independent risk factors for death in patients with traumatic epilepsy,and should be paid attention to patients with brain injury.
出处
《国际检验医学杂志》
CAS
2017年第17期2399-2400,2403,共3页
International Journal of Laboratory Medicine
关键词
创伤性癫痫
血浆前清蛋白
自我效能
生活质量
预后
traumatic epilepsy
plasma pre-albumin
self efficacy
quality of life
prognosis
