摘要
目的:研究补阳还五汤加味对冠心病经皮冠状动脉介入(PCI)术后气虚血瘀证患者血脂以及血液流变学指标的影响,以期为临床用药提供依据。方法:选取冠心病PCI术后气虚血瘀证患者68例,将患者随机分成两组,其中给予34例对照组患者常规西药治疗,34例治疗组患者在对照组治疗的基础上加用补阳还五汤加味。治疗3个月后,观察两组患者的临床疗效及血脂、血液流变学指标情况。结果:治疗3个月后,治疗组患者的临床治疗效果优于对照组(P<0.05),治疗组患者的TC、TG、LDL-C均低于对照组,HDL-C高于对照组(P<0.05),两组患者治疗后的全血高、中、低切黏度,血浆黏度、红细胞压积、纤维蛋白原均较治疗前有所改善(P<0.05),且治疗组改善程度优于对照组(P<0.05)。结论:补阳还五汤加味能有效改善冠心病PCI术后气虚血瘀证患者血脂及血液流变检测指标,提高其临床治疗效果。
Objective:To investigate and analysis of Buyang Huanwu decoction on effect of blood lipids and blood rheology in patients with Qi deficiency and blood stasis coronary heart disease after percutaneous coronary intervention(PCI)after operation,in order to provide the basis for clinical medication.Methods:68 cases were diagnosed in patients with Qi deficiency and blood stasis syndrome of coronary heart disease after PCI,randomly divided the patients into the two group.The control group received conventional western medicine treatment,the treatment group treated with Buyang Huanwu decoction based on the control group.After 3 years of treatment,the clinical efficacy,blood lipid and hemorheology of the patients in the two groups were observed.Results:After treatment in 3 months,the clinical effect of treatment of the treatment group is better thanand the control group(P<0.05),patients in the treatment group,TC,TG,LDL-C were lower than the control group,HDL-C was higher than the control group(P<0.05),whole blood shear viscosity,plasma viscosity,hematocrit and fibrinogen treatment group and control group after treatment were significantly improved(P<0.05),and the treatment group was better than the control group(P<0.05).Conclusion:Buyang Huanwu decoction can effectively improve blood lipid and blood rheology indexes of coronary heart disease patients after PCI,improve the clinical treatment effect,it is worthy of application in clinical treatment.
出处
《陕西中医》
2017年第9期1157-1159,共3页
Shaanxi Journal of Traditional Chinese Medicine