摘要
目的分析黑龙江省哈尔滨市甲状腺结节（TN）患病的危险因素。方法2014年11月至2015年1月，选取哈尔滨市南岗、道里、道外区居民及呼兰区许堡乡村民作为研究对象（均在当地居住超过5年），共2650例，进行一般性情况调查、临床检查及甲状腺超声检查，并通过Logistic回归分析进行各因素与TN关系的单因素、多因素分析。结果剔除有甲状腺手术史居民36例，TN总检出率为22．92％（599／2614），单因素Logistic回归分析显示，女性[比值比（OR）=1．597，95％置信区间（CI）=1．328～1．919]、老年（OR=3．356，95％CI：2．699—4．173）、城镇居住地（OR=1．677，95％CI=1．391—2．021）、肥胖（0R=1．245，95％CI=1．036—1．497）、有高血压史（OR=1．766，95％CI=1．414～2．205）是TN发病的危险因素。多因素Logistic回归分析显示，危险因素由高到低依次为老年（OR=3．076，95％（21=2．436～3．884）、女性（OR=1．819，95％CI=1．493—2．215）、城镇居住地（OR=1．701，95％CI=1．400～2．066）、有糖尿病史（OR=1．644，95％CI：1．235～2．189）、肥胖（OR=1．325，95％CI=1．085～1．618）。结论城镇居住地、老年、女性、肥胖、高血压史、糖尿病史是黑龙江省哈尔滨市居民TN发病的危险因素。
Objective To analyze the risk factors of thyroid nodule （TN） in Harbin City, Heilongjiang Province. Methods From November 2014 to January 2015, residents lived in Nangang, Daoli, Daowai districts and villagers of Xubao Town of Hulan District of Harbin City were selected as research subjects, who lived in the local regions for more than 5 years, a total of 2 650 people were surveyed. Influence factors of TN were surveyed by general survey, clinical examination and thyroid ultrasound examination. Logistie regression analysis was used to analyze relationships between various factors and TN in single factor analysis and multiple factors analysis. Results Excluding 36 eases with thyroid surgery history, the total prevalence of TN was 22.92% （599/2 614）, single factor Logistic regression analysis found that females [odds ratio （OR） = 1.597, 95% confidence interval （Co = 1.328 - 1.919], elderly （OR = 3.356, 95%CI = 2.699 - 4.173）, living in cities and towns （OR = 1.677, 95%CI = 1.391 - 2.021）, obesity （OR = 1.245, 95%CI = 1.036 - 1.497）, history of hypertension （OR = 1.766, 95%CI = 1.414 - 2.205） were the risk factors of TN. In multiple factors Logistic regression analysis, risk factors from high to low in the order were elderly （OR = 3.076, 95%CI = 2.436 - 3.884）, females （OR = 1.819, 95%CI = 1.493 - 2.215）, living in cities and towns （OR = 1.701, 95%CI = 1.400 - 2.066）, history of diabetes （OR = 1.644, 95%CI = 1.235 - 2.189）, obesity （OR = 1.325, 95%CI = 1.085 - 1.618）. Conclusions The risk factors of TN include living in eities and towns, females, elderly, obesity, history of hypertension or diabetes in Harbin City of Heilongjiang Province.
出处
《中华地方病学杂志》
CSCD
北大核心
2017年第9期675-678,共4页
Chinese Journal of Endemiology
