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关注儿童青少年钙磷代谢障碍相关性骨病和遗传性骨病 被引量:7

Paying attention to the bone diseases related to metabolic disorder of calcium and phosphorus and genetic bone diseases
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摘要 儿童青少年时期是骨骼生长发育和骨质矿化的关键阶段。儿童青少年骨病可导致骨骼畸形,影响成人期峰值骨量及身高。因此,早期识别并治疗儿童青少年骨病具有重要意义。根据临床表现及实验室检查结果,儿童青少年骨病可分为钙磷代谢障碍相关性骨病和遗传性骨病。该文对常见的钙磷代谢障碍相关性骨病和遗传性骨病的发病机制、临床表现、生化特点、影像学特征、检测及治疗进行了总结及评述。 Childhood and adolescence are key periods for bone development and mineralization. Bone diseases in child- hood and adolescence can result in skeleton deformities, decreased adult height and changed peak bone mass. It would be very important to early diagnose and treat bone diseases in childhood and adolescence. According to the clinical mani- festation, laboratory examinations and X-ray, bone diseases can be classified as metabolic bone disorders of calcium and phosphate, and genetic bone diseases. The pathogenesis, clinical manifestations, biochemical and radiological features of bone disease in childhood and adolescence were summarized. Progress in radiological examinations and treatment of these diseases were reviewed.
作者 梁雁 罗小平
出处 《中国实用儿科杂志》 CSCD 北大核心 2017年第9期649-654,共6页 Chinese Journal of Practical Pediatrics
关键词 骨病 代谢性骨病 遗传性骨病 bone disease metabolic bone disease genetic bone disease
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