摘要
类风湿关节炎(RA)的发病机制目前仍不清楚,其发病涉及复杂的免疫机制,多种免疫细胞、细胞因子。近年来研究发现白介素-17(IL-17)在RA患者中异常升高,与RA的滑膜炎症、软骨和骨的破坏有关。本文对近年来IL-17在RA发病机制中的作用进行综述。
The pathogenesis of Rheumatoid Arthritis (RA) is still uncertain for the pathogenesis of RA involves complex immune mechanisms, a variety of immune cells and cytokines. In recent years, studies have showed that interleukin-17 (IL-17) elevated abnormally in RA patients, which is related to RA synovial in- flammation, cartilage and bone destruction. This review summarizes the function of IL-17 in the pathogenesis of RA in recent years.
作者
张小玲
王秋燚
姚血明
宁乔怡
周静
黄颖
马武开
ZHANG Xiao-Ling WANG Qiu-yi YAO Xue-Ming NING Qiao-Yi ZHOU Jing HUANG Ying MA Wu-kai(Department of Rheumatology, the Second Affiliated Hospital of Guiyang University of Chinese Medicine, Guiyang 550003, Guizhou Chin)
出处
《贵阳中医学院学报》
2017年第5期91-94,共4页
Journal of Guiyang University of Chinese Medicine
基金
国家自然科学基金项目
项目编号:81360580
贵州省高层次创新型人才培养计划-"百"层次人才项目
项目编号:20165650
贵州省民族医学特色重点学科项目
项目编号:ZDXK[20157]